Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4708394 | 0.82 | RXFP1 (0.44) | ALDH1A1HPGDSMN1; SMN2GAAKCNH2 | |
| SCHEMBL4637891 | 0.78 | TACR1 (0.39) | TACR1CNR2KCNH2NPC1RAB9A | |
| SCHEMBL14144832 | 0.78 | TACR1 (0.37) | ALDH1A1SMN1; SMN2TACR1MAPT | |
| SCHEMBL27603336 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HPGDSMN1; SMN2TACR1CNR2 | |
| SCHEMBL4708291 | 0.76 | HPGD (0.39) | ALDH1A1HPGDSMN1; SMN2GAAKCNH2 | |
| SCHEMBL4637694 | 0.75 | EPAS1 (0.39) | ALDH1A1SMN1; SMN2GAATACR1NTRK1 | |
| SCHEMBL4707874 | 0.75 | EPAS1 (0.39) | ALDH1A1SMN1; SMN2GAAKDM4EMAPT | |
| SCHEMBL4708316 | 0.75 | TACR1 (0.33) | ALDH1A1SMN1; SMN2GAATACR1CNR2 | |
| SCHEMBL4637876 | 0.75 | EPAS1 (0.39) | ALDH1A1SMN1; SMN2GAATACR1NTRK1 | |
| SCHEMBL4637845 | 0.75 | EPAS1 (0.41) | ALDH1A1SMN1; SMN2GAATACR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239776-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239776-A1 | Tachykinin receptor antagonists | TACR2, TACR1, PROKR1 | ALDH1A1 1988/4885HPGD 1369/4885SMN1; SMN2 2813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.