Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4859939 | 0.99 | KDM4E (0.57) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL4852892 | 0.95 | KDM4E (0.52) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL4849870 | 0.94 | HTR1A (0.57) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| SCHEMBL4250223 | 0.92 | HTR1A (0.59) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL4856005 | 0.91 | HTR1A (0.58) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL4857814 | 0.90 | HTR1A (0.54) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL4852289 | 0.90 | HTR1A (0.57) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL4858384 | 0.89 | KDM4E (0.57) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL4852985 | 0.88 | KDM4E (0.56) | KDM4ELMNAHTR1AADRA1BDRD2 | |
| SCHEMBL14064640 | 0.86 | KDM4E (0.53) | KDM4ELMNAHTR1AADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261291-A1 | 1,2-Di(cyclic)substituted benzene compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261291-A1 | 1,2-Di(cyclic)substituted benzene compounds | CCR10, HRH3, HRH2 | KDM4E 3582/4885LMNA 4842/4885HTR1A 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.