Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MBD2 | Q9UBB5 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5659240 | 0.71 | BIRC5 (0.57) | SCN2AALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL3834819 | 0.69 | FGFR1 (0.72) | ALDH1A1MAPTFGFR1 | |
| SCHEMBL3107098 | 0.68 | ATM (0.55) | SCN2AALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL85578 | 0.68 | SCN2A (0.54) | SCN2AALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL29525910 | 0.68 | ATM (0.55) | SCN2AALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6303518 | 0.68 | MAPT (0.50) | SCN2AALDH1A1LMNAMAPTRAB9A | |
| SCHEMBL6298926 | 0.66 | ALDH1A1 (0.67) | SCN2AALDH1A1LMNAMAPTFGFR1 | |
| SCHEMBL5309437 | 0.66 | HTT (0.39) | SCN2AALDH1A1MAPTFGFR1MEN1 | |
| Nitrobenzene SCHEMBL7748458 | 0.64 | ALDH1A1 (0.94) | ALDH1A1LMNARAB9AMEN1KMT2A | |
| Benzene SCHEMBL28311584 | 0.64 | ALDH1A1 (0.82) | ALDH1A1LMNAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919344-B2 | N-substituted indole-3-glyoxylamides having anti-asthmatic, antiallergic and immunosuppressant/immuno-modulating action | ASTA MEDICA, AKTIENGESELLSCHAFT (DE) | 2005-07-19 | — | — | US | disclosed |
| US-6344467-B1 | ANTIASTHMATIC, ANTIALLERGIC AND IMMUNOSUPPRESSANT/IMMUNOMODULATING PROPERTIES | ASTA MEDICA AG (DE) | 2002-02-05 | — | — | US | disclosed |