Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479617 | 0.84 | PDE2A (0.32) | HTR4 | |
| SCHEMBL6493704 | 0.82 | MAPK1 (0.34) | MAPK1 | |
| SCHEMBL6492854 | 0.79 | MAPK1 (0.34) | MAPK1HTR4 | |
| SCHEMBL588047 | 0.78 | MAPK1 (0.33) | MAPK1HTR4 | |
| SCHEMBL587146 | 0.77 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL587431 | 0.77 | MAPK1 (0.43) | MAPK1 | |
| SCHEMBL6480302 | 0.77 | MAPK1 (0.35) | MAPK1HTR4 | |
| SCHEMBL8493697 | 0.76 | DHODH (0.35) | — | |
| SCHEMBL588251 | 0.75 | MAPK1 (0.34) | MAPK1HTR4 | |
| SCHEMBL6489414 | 0.74 | CNR2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239829-A1 | Novel piperidine compound | TANABE SEIYAKU CO. LTD. (JP) | 2005-10-27 | — | — | US | disclosed |
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | YANAGI AKIHIKO (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1476437-A1 | NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES | Bayer CropScience AG (DE) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003066607-A1 | NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239829-A1 | Novel piperidine compound | EP300, BRD1, CBR3 | MAPK1 1339/4885HTR4 729/4885 |
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | DDT, TTI1, CYP1A1 | MAPK1 2914/4885HTR4 2541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.