SCHEMBL6480912

SCHEMBL6480912

O=C(CCCCC(Cl)(Cl)Cl)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
MAPT P10636 2/20 0.68
LMNA P02545 1/20 0.68
HDAC1 Q13547 7/20 0.61
HDAC8 Q9BY41 6/20 0.61
HDAC3 O15379 3/20 0.61
HDAC2 Q92769 3/20 0.61
HDAC4 P56524 2/20 0.61
HDAC7 Q8WUI4 2/20 0.61
HDAC10 Q969S8 2/20 0.61
HDAC11 Q96DB2 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
HDAC9 Q9UKV0 2/20 0.61
HDAC5 Q9UQL6 2/20 0.61
NPC1 O15118 1/20 0.55
CASP3 P42574 1/20 0.55
RAB9A P51151 1/20 0.55
SENP8 Q96LD8 1/20 0.55
SENP7 Q9BQF6 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27325595 0.86 TDP1 (0.57) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL7068671 0.84 TDP1 (0.95) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL1954185 0.83 TDP1 (0.59) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL27516050 0.82 TDP1 (1.00) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL8519287 0.82 TDP1 (1.00) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL9057671 0.82 TDP1 (1.00) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL3856592 0.81 TDP1 (0.68) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL1052631 0.80 TDP1 (0.86) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL7889843 0.79 TDP1 (0.76) TDP1L3MBTL1MAPTLMNAHDAC1
SCHEMBL2238406 0.79 TDP1 (0.76) TDP1L3MBTL1MAPTLMNAHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12448487-B2 Polysiloxanes with radiation- and moisture-cross-linkable groups WACKER CHEMIE AG (DE) 2025-10-21 US disclosed
CN-115397891-B Polysiloxanes with radiation-crosslinkable and moisture-crosslinkable groups 瓦克化学股份公司 2024-02-02 CN disclosed
US-20230167246-A1 Polysiloxanes with radiation- and moisture-cross-linkable groups WACKER CHEMIE AG (DE) 2023-06-01 US disclosed
EP-4136137-A1 POLYSILOXANES WITH RADIATION- AND MOISTURE-CROSS-LINKABLE GROUPS Wacker Chemie AG (DE) 2023-02-22 EP disclosed
WO-2021209113-A1 POLYSILOXANES WITH RADIATION- AND MOISTURE-CROSS-LINKABLE GROUPS WACKER CHEMIE AG (DE) 2021-10-21 WO disclosed
WO-2021044261-A1 SPATIALLY CONTROLLED FUNCTIONALITY OF POLYMERIC PRODUCTS NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2021-03-11 WO disclosed
US-6846852-B2 Siloxane-containing compositions curable by radiation to silicone elastomers GOLDSCHMIDT AG (DE) 2005-01-25 US disclosed
US-20030064232-A1 Siloxane-containing compositions curable by radiation to silicone elastomers EVONIK GOLDSCHMIDT GMBH (DE) 2003-04-03 US disclosed
WO-2003016403-A1 SILOXANE-CONTAINING COMPOSITIONS CURABLE BY RADIATION TO SILICONE ELASTOMERS GOLDSCHMIDT AG (DE) 2003-02-27 WO disclosed
EP-0590020-B1 CURABLE ORGANOPOLYSILOXANE PREPARATIONS WACKER CHEMIE GMBH (DE) 1995-09-06 EP disclosed
EP-0169295-B1 POLYSILOXANES, PROCESS FOR PREPARING THEM AND THEIR USE Wacker-Chemie GmbH (DE) 1988-06-15 EP disclosed
EP-0237757-A2 Compositions convertible into elastomers by irradiation Wacker-Chemie GmbH (DE) 1987-09-23 EP disclosed
US-4605567-A PHOTOPOLYMERIZATION OF ALLYL ANHYDRIDE-MODIFIED POLYSILOXANES REACTED WITH HYDROXYETHYL ACRYLATE WACKER-CHEMIE GMBH (DE) 1986-08-12 US disclosed
EP-0186099-A2 Crosslinkable organopolysiloxanes, process for their preparation and use of these organopolysiloxanes Wacker-Chemie GmbH (DE) 1986-07-02 EP disclosed
US-4597987-A Organopolysiloxanes containing both acryloxyalkyl groups and Si-bonded hydrogen atoms in the same molecule WACKER-CHEMIE GMBH (DE) 1986-07-01 US disclosed
US-4571349-A Crosslinkable organopolysiloxanes and a method for preparing the same WACKER-CHEMIE GMBH (DE) 1986-02-18 US disclosed
EP-0169295-A2 Polysiloxanes, process for preparing them and their use Wacker-Chemie GmbH (DE) 1986-01-29 EP disclosed
US-4554339-A PROTECTIVE COATINGS, SILICON-BONDED HYDROGEN WACKER-CHEMIE GMBH (DE) 1985-11-19 US disclosed
EP-0156036-A2 Organopolysiloxanes and by light irradiation crosslinkable materials containing these polysiloxanes Wacker-Chemie GmbH (DE) 1985-10-02 EP disclosed
EP-0097333-A2 Organopolysiloxanes, process for their production and their use Wacker-Chemie GmbH (DE) 1984-01-04 EP disclosed