Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.76 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.68 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.68 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.68 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.68 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.68 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.68 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633948 | 0.98 | TDP1 (0.80) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL633401 | 0.98 | TDP1 (0.80) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL2236826 | 0.98 | TDP1 (0.80) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL318784 | 0.94 | TDP1 (0.72) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL29506825 | 0.92 | TDP1 (0.69) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| Ethylene SCHEMBL10973512 | 0.90 | TDP1 (0.67) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL7068671 | 0.89 | TDP1 (0.95) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL6610437 | 0.89 | HDAC1 (0.64) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| Acetic Acid SCHEMBL2763001 | 0.88 | L3MBTL1 (0.64) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| Ethylene Glycol SCHEMBL11544664 | 0.88 | TDP1 (0.64) | TDP1L3MBTL1MAPTLMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | INFINEUM INTERNATIONAL LIMITED (GB) | 2024-08-29 | — | — | US | disclosed |
| EP-4410772-A2 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | Infineum International Limited (GB) | 2024-08-07 | — | — | EP | disclosed |
| CN-118440229-A | Amine functional monomers and methods of making the same | 英菲诺姆国际有限公司 | 2024-08-06 | — | — | CN | disclosed |
| US-11730705-B2 | Small molecule CMKLR1 antagonists in inflammatory disease | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| US-11730705-B2 | Small molecule CMKLR1 antagonists in inflammatory disease | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-08-22 | — | — | US | disclosed |
| US-20200345661-A1 | SMALL MOLECULE CMKLR1 ANTAGONISTS IN INFLAMMATORY DISEASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2020-11-05 | — | — | US | disclosed |
| EP-2947066-B1 | PHENOXYALKYLAMINE COMPOUND | UNIV OSAKA (JP) | 2018-09-19 | — | — | EP | disclosed |
| US-9771316-B2 | Phenoxyalkylamine compound | OSAKA UNIVERSITY (JP) | 2017-09-26 | — | — | US | disclosed |
| US-9693974-B2 | Antibacterial and antifungal biphenylyl compounds | CHRISTIAN-ALBRECHTS-UNIVERSITY OF KIEL (DE) | 2017-07-04 | — | — | US | disclosed |
| US-20150336876-A1 | PHENOXYALKYLAMINE COMPOUND | KNC LABORATORIES CO., LTD. (JP) | 2015-11-26 | — | — | US | disclosed |
| EP-0673362-A1 | ARALKYLDIAMINE DERIVATIVES AND ANTIARRYTHMIC DRUGS CONTAINING THEM | Helopharm W. Petrik GmbH & Co.KG. (DE) | 1995-09-27 | — | — | EP | disclosed |
| WO-1994013622-A1 | ARALKYLDIAMINE DERIVATIVES AND ANTIARRYTHMIC DRUGS CONTAINING THEM | HELOPHARM W. PETRIK GMBH & CO. KG. (DE) | 1994-06-23 | — | — | WO | disclosed |
| EP-0069536-B1 | PHLOROPHENONE DERIVATIVES, PROCESSES FOR PREPARING SUCH COMPOUNDS, USES AND PHARMACEUTICAL COMPOSITIONS OF PHLOROPHENONE COMPOUNDS | NORISTAN LIMITED (ZA) | 1986-12-17 | — | — | EP | disclosed |
| US-4578520-A | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1986-03-25 | — | — | US | disclosed |
| US-4503256-A | BACTERICIDES, FUNGICIDES | NORISTAN LIMITED (ZA) | 1985-03-05 | — | — | US | disclosed |
| EP-0035228-B1 | TETRAZOLE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF, AND ANTI-ULCER COMPOSITION CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-01-02 | — | — | EP | disclosed |
| US-4372953-A | Tetrazole derivatives, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-02-08 | — | — | US | disclosed |
| EP-0069536-A1 | Phlorophenone derivatives, processes for preparing such compounds, uses and pharmaceutical compositions of phlorophenone compounds | NORISTAN LIMITED (ZA) | 1983-01-12 | — | — | EP | disclosed |
| EP-0035228-A1 | Tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |
| US-3946022-A | ANTIHISTAMINES, ANTIALLERGENS, BRONCHODILATORS | RICHARDSON-MERRELL INC. (US) | 1976-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336876-A1 | PHENOXYALKYLAMINE COMPOUND | LATS1, LATS2, SHC1 | TDP1 3430/4885L3MBTL1 560/4885MAPT 1201/4885 |
| US-20240287009-A1 | AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME | AMD1, HNMT, MAT1A | TDP1 110/4885L3MBTL1 1448/4885MAPT 2352/4885 |
| US-20200345661-A1 | SMALL MOLECULE CMKLR1 ANTAGONISTS IN INFLAMMATORY DISEASE | CMKLR1, CMKLR2, IL1RN | TDP1 2084/4885L3MBTL1 2724/4885MAPT 902/4885 |
| US-11730705-B2 | Small molecule CMKLR1 antagonists in inflammatory disease | CMKLR1, CMKLR2, IL1RN | TDP1 2084/4885L3MBTL1 2724/4885MAPT 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.