Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536507 | 0.83 | TSHR (0.46) | TSHRMAOBNPSR1KCNH2CDK4 | |
| SCHEMBL8118478 | 0.82 | TSHR (0.48) | TSHRALDH1A1LMNAPOLB | |
| SCHEMBL916350 | 0.81 | CCNT1 (0.43) | TSHRNPSR1KCNH2ALDH1A1LMNA | |
| SCHEMBL27283372 | 0.80 | TSHR (0.46) | TSHRMAOBALDH1A1LMNAFFAR1 | |
| SCHEMBL5775184 | 0.78 | MAOB (0.45) | MAOBCDK4CCND1ALDH1A1ACHE | |
| SCHEMBL8110217 | 0.78 | ALDH1A1 (0.50) | TSHRNPSR1ALDH1A1 | |
| SCHEMBL11155015 | 0.78 | MAOB (0.37) | MAOBCDK4CCND1 | |
| SCHEMBL1238316 | 0.77 | TSHR (0.56) | TSHRNPSR1KCNH2ALDH1A1LMNA | |
| SCHEMBL11744417 | 0.77 | ALDH1A1 (0.46) | TSHRMAOBALDH1A1LMNAACHE | |
| SCHEMBL716503 | 0.76 | AGXT (0.42) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2005-05-05 | — | — | US | disclosed |
| US-20030224206-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. | 2003-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096491-A1 | Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element | OR51E2, CYP4F11, ACAD11 | TSHR 3245/4885MAOB 1092/4885NPSR1 3027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.