Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 7/20 | 0.63 |
| ▸ | NPY1R | P25929 | 6/20 | 0.63 |
| ▸ | NPY2R | P49146 | 5/20 | 0.63 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.59 |
| ▸ | IL1RN | P18510 | 1/20 | 0.57 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 10/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6481539 | 1.00 | NPY4R (0.63) | NPY4RNPY1RNPY2RNPY5RIL1RN | |
| SCHEMBL30567424 | 0.98 | NPY4R (0.60) | NPY4RNPY1RNPY2RNPY5RIL1RN | |
| SCHEMBL29577262 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL1RN | |
| SCHEMBL29577231 | 0.98 | NPY4R (0.62) | NPY4RNPY1RNPY2RNPY5RIL1RN | |
| SCHEMBL29511101 | 0.95 | KISS1R (0.58) | NPY4RNPY1RNPY2RIL1RNERAP2 | |
| SCHEMBL29672131 | 0.95 | NPY1R (0.56) | NPY4RNPY1RNPY2RKISS1R | |
| SCHEMBL30186443 | 0.95 | KISS1R (0.60) | NPY4RNPY1RNPY2RIL1RNERAP2 | |
| SCHEMBL31511497 | 0.94 | NPY4R (0.58) | NPY4RNPY1RNPY2RNPY5RIL1RN | |
| SCHEMBL30919251 | 0.94 | NPY1R (0.56) | NPY4RNPY1RNPY2RKISS1R | |
| SCHEMBL31074784 | 0.94 | KMT2A (0.55) | NPY4RNPY1RNPY2RKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6953779-B2 | Melanocortin receptor antagonists and modulations of melanocortin receptor activity | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-10-11 | — | — | US | disclosed |