SCHEMBL6483716

SCHEMBL6483716

CCCCC(NC(=O)C(C)(C)N)C(=O)NCc1ccc(-c2ccccc2-c2nnn[nH]2)cc1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NPY1R P25929 5/20 0.38
CTSK P43235 1/20 0.38
LTB4R2 Q9NPC1 1/20 0.37
CTSL P07711 1/20 0.36
CTSS P25774 1/20 0.36
EHMT2 Q96KQ7 1/20 0.36
GHSR Q92847 1/20 0.36
MCHR1 Q99705 1/20 0.36
AGTR1 P30556 2/20 0.36
MME P08473 1/20 0.36
SPHK1 Q9NYA1 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
TLR2 O60603 1/20 0.35
NPY4R P50391 2/20 0.35
NPY5R Q15761 1/20 0.35
AGTR2 P50052 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8792328 0.92 NPY1R (0.43) NPY1RCTSKCTSSGHSRMCHR1
SCHEMBL8794950 0.90 PSMB5 (0.42) NPY1RCTSKCTSSGHSR
SCHEMBL6480737 0.87 LTB4R2 (0.35) NPY1RCTSKLTB4R2AGTR1MME
SCHEMBL6496156 0.86 GHSR (0.34) CTSKLTB4R2GHSRAGTR1MMP3
SCHEMBL6481904 0.85 NPY1R (0.41) NPY1RLTB4R2CTSLCTSSEHMT2
SCHEMBL8790297 0.84 GHSR (0.47) CTSSGHSR
SCHEMBL6482720 0.84 GHSR (0.47) CTSSGHSR
SCHEMBL6482170 0.83 SIRT2 (0.38) NPY1RLTB4R2CTSLCTSSEHMT2
SCHEMBL8793511 0.83 NPY1R (0.45) NPY1RCTSLMCHR1MMP3NPY4R
SCHEMBL6491342 0.82 GHSR (0.53) CTSKCTSLCTSSGHSRMMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050261332-A1 Sulfonamides and uses thereof ELIXIR PHARMACEUTICALS, INC. 2005-11-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261332-A1 Sulfonamides and uses thereof GLS2, STS, ABAT NPY1R 2810/4885CTSK 2319/4885LTB4R2 2432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.