Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.62 |
| ▸ | PPARG | P37231 | 5/20 | 0.60 |
| ▸ | PPARA | Q07869 | 4/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.59 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289659 | 0.90 | MAOB (0.61) | MAOBPPARGPPARAALOX5PPARD | |
| SCHEMBL16743935 | 0.90 | MAOB (0.61) | MAOBPPARGPPARAALOX5PPARD | |
| SCHEMBL20363249 | 0.87 | MAOB (0.57) | MAOBPPARGPPARAALOX5PPARD | |
| SCHEMBL20905985 | 0.86 | CYP2D6 (0.56) | MAOBALOX5FFAR1 | |
| SCHEMBL10790060 | 0.85 | ITGB3 (0.66) | MAOBPPARGPPARAALOX5PPARD | |
| SCHEMBL3803671 | 0.84 | PPARG (0.59) | MAOBPPARGPPARAALOX5PPARD | |
| SCHEMBL121727 | 0.84 | MAPT (0.61) | PPARGPTGS1L3MBTL1 | |
| SCHEMBL756362 | 0.84 | MAPT (0.61) | PPARGPTGS1L3MBTL1 | |
| SCHEMBL121728 | 0.84 | MAPT (0.61) | PPARGPTGS1L3MBTL1 | |
| SCHEMBL19930028 | 0.83 | MAOB (0.63) | MAOBPPARGPPARAALOX5PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916812-B2 | Dietetic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-12 | — | — | US | disclosed |
| US-20030232807-A1 | Alpha-aminoamide derivatives as melanocortin agonists | POINDEXTER GRAHAM S (US) | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232807-A1 | Alpha-aminoamide derivatives as melanocortin agonists | MC1R, MC5R, MC4R | MAOB 1504/4885PPARG 528/4885PPARA 749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.