Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6482915 | 0.95 | CYSLTR2 (0.43) | CYSLTR2CYSLTR1KDM1AIDO1TDO2 | |
| SCHEMBL6475547 | 0.93 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1 | |
| SCHEMBL6484332 | 0.93 | KIF11 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL6476335 | 0.92 | EPHX2 (0.42) | CYSLTR2CYSLTR1IDO1TDO2 | |
| SCHEMBL6477763 | 0.92 | IDO1 (0.41) | CYSLTR2CYSLTR1IDO1TDO2 | |
| SCHEMBL6483514 | 0.91 | CYP3A4 (0.40) | CYSLTR2CYSLTR1 | |
| SCHEMBL6477739 | 0.89 | CYSLTR2 (0.40) | CYSLTR2CYSLTR1KDM1AIDO1TDO2 | |
| SCHEMBL6487120 | 0.88 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1IDO1TDO2 | |
| SCHEMBL6488956 | 0.87 | AGXT (0.42) | CYSLTR2CYSLTR1KDM1A | |
| SCHEMBL6489349 | 0.87 | CYSLTR2 (0.42) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6933322-B2 | Substituted naphthylenes for the treatment of non-insulin dependent diabetes mellitus | WYETH (US) | 2005-08-23 | — | — | US | disclosed |