SCHEMBL6485939

SCHEMBL6485939

CCc1ccc(C(=N)c2ccc(CC)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.54
IDO1 P14902 2/20 0.50
PLK1 P53350 1/20 0.50
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
HBB P68871 1/20 0.44
TP53 P04637 2/20 0.43
TDP1 Q9NUW8 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
NQO2 P16083 1/20 0.42
PLAU P00749 1/20 0.41
TAS1R3 Q7RTX0 1/20 0.41
TAS1R1 Q7RTX1 1/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10606092 0.91 TP53 (0.54) ALDH1A1SMN1; SMN2IDO1PLK1LPL
SCHEMBL13295554 0.85 TSHR (0.70) ALDH1A1SMN1; SMN2IDO1PLK1CYP3A4
SCHEMBL24815652 0.84 PRSS1 (0.50) ALDH1A1SMN1; SMN2IDO1PLK1ALOX15
SCHEMBL10308978 0.82 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2IDO1PLK1LPL
SCHEMBL1696572 0.80 PRSS1 (0.64) ALDH1A1SMN1; SMN2IDO1NQO2PLAU
SCHEMBL13944771 0.80 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2IDO1PLK1LPL
Hydrochloric Acid SCHEMBL11567719 0.78 PRSS1 (0.61) ALDH1A1SMN1; SMN2IDO1NQO2PLAU
SCHEMBL22084114 0.77 PLK1 (0.53) ALDH1A1SMN1; SMN2IDO1PLK1LPL
SCHEMBL13455846 0.77 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2IDO1PLK1LPL
SCHEMBL18975457 0.77 PLK1 (0.59) ALDH1A1SMN1; SMN2IDO1PLK1LPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890377-B2 Thermochromic rylene dyes BASF AKTIENGESELLSCHAFT (DE) 2005-05-10 US disclosed
US-20040089199-A1 Thermochromic rylene dyes BASF AKTIENGESELLSCHAFT (DE) 2004-05-13 US disclosed
US-6486319-B1 Thermochromic rylene dyes BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed