Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 9/20 | 0.89 |
| ▸ | CA12 | O43570 | 2/20 | 0.89 |
| ▸ | CA1 | P00915 | 2/20 | 0.89 |
| ▸ | CA2 | P00918 | 2/20 | 0.89 |
| ▸ | CA3 | P07451 | 2/20 | 0.89 |
| ▸ | CA4 | P22748 | 2/20 | 0.89 |
| ▸ | CA6 | P23280 | 2/20 | 0.89 |
| ▸ | CA5A | P35218 | 2/20 | 0.89 |
| ▸ | CA7 | P43166 | 2/20 | 0.89 |
| ▸ | CA9 | Q16790 | 2/20 | 0.89 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.89 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.89 |
| ▸ | TSHR | P16473 | 2/20 | 0.89 |
| ▸ | LMNA | P02545 | 1/20 | 0.89 |
| ▸ | BLM | P54132 | 1/20 | 0.89 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL29052692 | 1.00 | DNM1 (0.89) | DNM1CA12CA1CA2CA3 | |
| Ethylenediamine SCHEMBL28326970 | 0.95 | DNM1 (0.80) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL887774 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL7189680 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 | |
| Diaminooctane SCHEMBL8650707 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL25262966 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL22684930 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL22283336 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL22684932 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 | |
| Putrescine SCHEMBL7698565 | 0.94 | DNM1 (1.00) | DNM1CA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117512719-A | Hole filling copper plating process and application | 中山博美新材料科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| US-8119251-B2 | Polyamides | HENKEL CORPORATION (US) | 2012-02-21 | — | — | US | claimed |
| US-6863797-B2 | Electrolyte with good planarization capability, high removal rate and smooth surface finish for electrochemically controlled copper CMP | APPLIED MATERIALS, INC. (US) | 2005-03-08 | — | — | US | claimed |
| EP-4370329-A1 | ONE-COMPONENT MOISTURE-CURABLE ADHESIVE COMPOSITION | Akzo Nobel Coatings International B.V. (NL) | 2024-05-22 | — | — | EP | disclosed |
| CN-117512719-A | Hole filling copper plating process and application | 中山博美新材料科技有限公司 | 2024-02-06 | — | — | CN | disclosed |
| WO-2023285561-A1 | ONE-COMPONENT MOISTURE-CURABLE ADHESIVE COMPOSITION | AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) | 2023-01-19 | — | — | WO | disclosed |
| US-11384202-B2 | Water-soluble polyamide polymer and use thereof as functional additive | HENKEL AG & CO. KGAA (DE) | 2022-07-12 | — | — | US | disclosed |
| CN-114217486-A | Electrochromic material, preparation method thereof and electrochromic device | 深圳市志凌伟业光电有限公司 | 2022-03-22 | — | — | CN | disclosed |
| US-11248143-B2 | Coated films and electronic devices | DUPONT ELECTRONICS, INC. (US) | 2022-02-15 | — | — | US | disclosed |
| CN-113274506-A | Drug delivery technology of polymer-carbohydrate conjugates | 念·吴 | 2021-08-20 | — | — | CN | disclosed |
| US-20200369913-A1 | COATED FILMS AND ELECTRONIC DEVICES | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2020-11-26 | — | — | US | disclosed |
| US-5120816-A | Reaction product of the mixture of long chain and medium chain polyoxyethylene glycol, chain extender, water and diisocyanate | TYNDALE PLAINS-HUNTER LTD. (US) | 1992-06-09 | — | — | US | disclosed |
| US-5061424-A | Coextruding melt of substrate polymer and a blend of polyvinyl pyrrolidone and polyurethane coating composition which absorbs water when wetted to become lubricious | BECTON, DICKINSON AND COMPANY (US) | 1991-10-29 | — | — | US | disclosed |
| US-4990357-A | Biocompatible uniform blend for coating a substrate | BECTON, DICKINSON AND COMPANY (US) | 1991-02-05 | — | — | US | disclosed |
| EP-0400015-A4 | HYDROPHILIC POLYURETHANES OF IMPROVED STRENGTH | — | 1991-01-16 | — | — | EP | disclosed |
| EP-0400015-A1 | HYDROPHILIC POLYURETHANES OF IMPROVED STRENGTH | TYNDALE PLAINS-HUNTER, LTD. (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0396431-A1 | Elastomeric segmented hydrophilic polyetherurethane based lubricious coatings | Becton, Dickinson and Company (US) | 1990-11-07 | — | — | EP | disclosed |
| WO-1989005319-A1 | HYDROPHILIC POLYURETHANES OF IMPROVED STRENGTH | TYNDALE PLAINS-HUNTER, LTD. (US) | 1989-06-15 | — | — | WO | disclosed |
| US-4732929-A | Silicon-containing polyols | PPG INDUSTRIES, INC. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4256818-A | Magnetic or electrostatographic imaging and high speed fusing method uses polyamide resin in toner | XEROX CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |