SCHEMBL6486178

SCHEMBL6486178

CCOc1ccc(C(=N)c2ccc(OCC)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.70
PRSS2 P07478 1/20 0.70
PRSS3 P35030 1/20 0.70
NQO1 P15559 1/20 0.64
PARP10 Q53GL7 1/20 0.59
NPC1 O15118 2/20 0.55
PLK1 P53350 1/20 0.55
TSHR P16473 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
LTA4H P09960 2/20 0.52
PLA2G4B P0C869 1/20 0.52
KMT2A Q03164 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.50
KDM4E B2RXH2 2/20 0.50
RAB9A P51151 1/20 0.50
MAPT P10636 1/20 0.50
ALOX15 P16050 1/20 0.50
RECQL P46063 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16798258 0.89 PRSS1 (0.58) PRSS1PRSS2PRSS3NQO1PARP10
SCHEMBL428950 0.83 PRSS1 (1.00) PRSS1PRSS2PRSS3PARP10
Hydrochloric Acid SCHEMBL11613449 0.81 PRSS1 (0.96) PRSS1PRSS2PRSS3PARP10
SCHEMBL17826827 0.81 PRSS1 (0.63) PRSS1PRSS2PRSS3NQO1PARP10
1,4-Diethoxybenzene SCHEMBL124015 0.80 NQO1 (1.00) PRSS1PRSS2PRSS3NQO1PARP10
1,4-Diethoxybenzene SCHEMBL28186701 0.80 NQO1 (1.00) PRSS1PRSS2PRSS3NQO1PARP10
SCHEMBL7753257 0.79 NQO1 (0.67) PRSS1PRSS2PRSS3NQO1PARP10
SCHEMBL1465950 0.78 PARP10 (0.66) PRSS1PRSS2PRSS3NQO1PARP10
SCHEMBL6961256 0.78 PRSS1 (0.65) PRSS1PRSS2PRSS3NQO1PARP10
SCHEMBL12054741 0.78 PRSS1 (0.59) PRSS1PRSS2PRSS3NQO1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6890377-B2 Thermochromic rylene dyes BASF AKTIENGESELLSCHAFT (DE) 2005-05-10 US disclosed
US-20040089199-A1 Thermochromic rylene dyes BASF AKTIENGESELLSCHAFT (DE) 2004-05-13 US disclosed
US-6486319-B1 Thermochromic rylene dyes BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed