Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CTSA | P10619 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28780278 | 0.92 | SMN1; SMN2 (0.39) | FFAR1SMN1; SMN2NPSR1RXFP1MAPT | |
| SCHEMBL688247 | 0.92 | SMN1; SMN2 (0.39) | FFAR1SMN1; SMN2NPSR1RXFP1MAPT | |
| SCHEMBL687654 | 0.88 | PTGER3 (0.43) | SMN1; SMN2MAPTKDM4ECYP1A2KMT2A | |
| SCHEMBL687573 | 0.86 | SMN1; SMN2 (0.38) | FFAR1SMN1; SMN2MAPTKDM4ECYP1A2 | |
| SCHEMBL27762477 | 0.85 | SMN1; SMN2 (0.39) | SMN1; SMN2NPSR1MAPTKDM4ECYP1A2 | |
| SCHEMBL687324 | 0.82 | PTGER3 (0.41) | SMN1; SMN2NPSR1RXFP1MAPTKDM4E | |
| SCHEMBL687970 | 0.81 | SMN1; SMN2 (0.41) | FFAR1SMN1; SMN2NPSR1RXFP1KDM4E | |
| SCHEMBL27741947 | 0.81 | SMN1; SMN2 (0.41) | FFAR1SMN1; SMN2NPSR1RXFP1KDM4E | |
| SCHEMBL687251 | 0.81 | PTGER3 (0.42) | SMN1; SMN2RXFP1MAPTCYP1A2PTGER3 | |
| SCHEMBL688172 | 0.81 | MAPT (0.41) | SMN1; SMN2NPSR1RXFP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6972296-B2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-12-06 | — | — | US | claimed |