Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1913061 | 0.89 | C5AR1 (0.38) | C5AR1ALDH1A1HTT | |
| SCHEMBL651033 | 0.88 | C5AR1 (0.44) | C5AR1ALDH1A1HTTTSHR | |
| SCHEMBL651956 | 0.87 | C5AR1 (0.43) | C5AR1ALDH1A1HTTTSHR | |
| SCHEMBL649152 | 0.86 | C5AR1 (0.47) | C5AR1 | |
| SCHEMBL648790 | 0.86 | C5AR1 (0.43) | C5AR1ALDH1A1HTTTSHR | |
| SCHEMBL650580 | 0.85 | C5AR1 (0.41) | C5AR1ALDH1A1HTTTSHR | |
| SCHEMBL5135971 | 0.85 | C5AR1 (0.41) | C5AR1ALDH1A1HTTTSHR | |
| SCHEMBL652505 | 0.84 | C5AR1 (0.42) | C5AR1ALDH1A1HTTTSHR | |
| SCHEMBL648409 | 0.84 | C5AR1 (0.42) | C5AR1ALDH1A1HTTTSHR | |
| SCHEMBL649675 | 0.84 | C5AR1 (0.42) | C5AR1ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306152-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LBORATORIES, INC. (US) | 2008-12-11 | — | — | US | claimed |
| EP-1651202-A4 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LAB INC (US) | 2006-08-02 | — | — | EP | claimed |
| EP-1651202-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2005009429-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2005-02-03 | — | — | WO | claimed |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | IDEXX LABORATORIES, INC. | 2005-01-20 | — | — | US | claimed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-8119665-B2 | Aryl imidazoles and related compounds as C5a receptor modulators | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2012-02-21 | — | — | US | disclosed |
| US-8119667-B2 | Carbonates of fenicol antibiotics | SCHERING-PLOUGH ANIMAL HEALTH CORPORATION (US) | 2012-02-21 | — | — | US | disclosed |
| EP-1966129-B1 | CARBONATES OF FENICOL ANTIBIOTICS | SCHERING PLOUGH LTD (CH) | 2011-08-17 | — | — | EP | disclosed |
| US-7786167-B2 | Ester derivatives; in vivo saponification by endogenous enzymes; dosage efficiency | IDEXX LABORATORIES, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-7786167-B2 | Ester derivatives; in vivo saponification by endogenous enzymes; dosage efficiency | IDEXX LABORATORIES, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| EP-1651202-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| EP-1651202-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005009429-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| WO-2005009429-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | IDEXX LABORATORIES, INC. (US) | 2005-02-03 | — | — | WO | disclosed |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | IDEXX LABORATORIES, INC. | 2005-01-20 | — | — | US | disclosed |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | IDEXX LABORATORIES, INC. | 2005-01-20 | — | — | US | disclosed |
| EP-1490044-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003084524-A1 | COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS | NEUROGEN CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306152-A1 | COMPOSITIONS CONTAINING PRODRUGS OF FLORFENICOL AND METHODS OF USE | FAP, CYP3A5, CYP4F3 | C5AR1 1670/4885ALDH1A1 178/4885HTT 3093/4885 |
| US-20050014828-A1 | Compositions containing prodrugs of florfenicol and methods of use | FAP, CYP3A5, CYP4F3 | C5AR1 1670/4885ALDH1A1 178/4885HTT 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.