Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.71 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 5/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6480922 | 0.88 | KCNH2 (0.68) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6489034 | 0.87 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9734892 | 0.87 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9733802 | 0.87 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10374229 | 0.87 | ALDH1A1 (0.67) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9522847 | 0.87 | ALDH1A1 (0.72) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9671640 | 0.87 | ALDH1A1 (0.72) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL6480467 | 0.86 | ALDH1A1 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9522683 | 0.86 | ALDH1A1 (0.71) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL14471355 | 0.85 | ALDH1A1 (0.76) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | claimed |
| WO-2005026165-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | claimed |
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107423-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | ALDH1A1 873/4885POLB 303/4885OPRM1 1709/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.