Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16058603 | 0.80 | CYP1A2 (0.38) | ATMLMNACYP2D6KMT2AGAA | |
| SCHEMBL295469 | 0.75 | ATM (0.43) | ATML3MBTL1LMNACYP2D6MEN1 | |
| SCHEMBL17896180 | 0.74 | ATM (0.40) | ATML3MBTL1LMNACYP2D6MEN1 | |
| SCHEMBL17896179 | 0.74 | ATM (0.40) | ATML3MBTL1LMNACYP2D6MEN1 | |
| SCHEMBL1252991 | 0.74 | LMNA (0.45) | LMNACYP2D6MEN1KMT2AMTNR1A | |
| SCHEMBL6490893 | 0.73 | ATM (0.33) | ATML3MBTL1KDM4E | |
| SCHEMBL15234013 | 0.73 | LMNA (0.39) | LMNAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL28663493 | 0.73 | LMNA (0.39) | ATMLMNAMEN1KMT2AMTNR1A | |
| SCHEMBL16671569 | 0.72 | LMNA (0.41) | LMNAMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL4248694 | 0.71 | LMNA (0.42) | ATML3MBTL1LMNACYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222247-A1 | Chroman derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222247-A1 | Chroman derivatives | CHRM3, CHRNB3, ADRB3 | ATM 2431/4885L3MBTL1 3998/4885LMNA 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.