Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BUB1 | O43683 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6479658 | 0.85 | POLB (0.34) | POLBF10NPC1MAPTRAB9A | |
| SCHEMBL6481052 | 0.84 | POLB (0.40) | POLBF10SMN1; SMN2BUB1ALDH1A1 | |
| SCHEMBL6481972 | 0.84 | POLB (0.40) | POLBF10NOTUM | |
| SCHEMBL6488316 | 0.82 | POLB (0.34) | POLBF10 | |
| SCHEMBL6481163 | 0.81 | POLB (0.33) | POLB | |
| SCHEMBL6605119 | 0.80 | POLB (0.33) | POLBF10MAPTKMT2A | |
| SCHEMBL6490664 | 0.79 | BUB1 (0.38) | NPC1MAPTRAB9ANFKB1NFKB2 | |
| SCHEMBL8818300 | 0.78 | HDAC1 (0.43) | POLBMAPTMEN1KMT2AHTT | |
| SCHEMBL6489376 | 0.78 | TP53 (0.43) | POLBF10NPC1MAPTRAB9A | |
| SCHEMBL6491262 | 0.75 | POLB (0.34) | POLBF10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | YANAGI AKIHIKO (JP) | 2005-04-28 | — | — | US | disclosed |
| EP-1476437-A1 | NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES | Bayer CropScience AG (DE) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003066607-A1 | NOVEL TETRAZOLE DERIVATIVE USEFUL AS HERBICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090398-A1 | Novel tetrazole derivative useful as herbicides | DDT, TTI1, CYP1A1 | POLB 3390/4885F10 2051/4885NPC1 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.