SCHEMBL648994

SCHEMBL648994

CCCCN(Cc1ccc2[nH]ccc2c1)Cc1c(C(F)(F)F)nc(-c2ccccc2)n1CCCC

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 16/20 0.44
C5AR1 P21730 1/20 0.39
BCHE P06276 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL650365 0.90 C5AR1 (0.45) CRHR1C5AR1BCHETSHR
SCHEMBL652681 0.88 C5AR1 (0.55) CRHR1C5AR1TSHR
SCHEMBL651125 0.88 CRHR1 (0.39) CRHR1C5AR1
SCHEMBL14572836 0.84 CRHR1 (0.49) CRHR1C5AR1BCHETSHR
SCHEMBL650037 0.84 CRHR1 (0.47) CRHR1C5AR1BCHETSHR
SCHEMBL14607057 0.83 CRHR1 (0.49) CRHR1C5AR1BCHETSHR
SCHEMBL651784 0.83 C5AR1 (0.46) CRHR1C5AR1BCHETSHR
SCHEMBL5135611 0.83 CRHR1 (0.49) CRHR1C5AR1TSHR
SCHEMBL649792 0.81 C5AR1 (0.62) CRHR1C5AR1TSHR
SCHEMBL1913039 0.81 CRHR1 (0.47) CRHR1C5AR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6476178-B1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 US claimed
US-12570837-B2 Polycarbonate resin composition and molded article IDEMITSU KOSAN CO., LTD. (JP) 2026-03-10 US disclosed
EP-4692233-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2026-02-11 EP disclosed
EP-3604443-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY IDEMITSU KOSAN CO (JP) 2025-10-15 EP disclosed
US-20250205637-A1 GAS SEPARATION MEMBRANE IDEMITSU KOSAN CO., LTD. (JP) 2025-06-26 US disclosed
EP-4556507-A1 POLYCARBONATE-POLYORGANOSILOXANE COPOLYMER, POLYCARBONATE RESIN COMPOSITION AND MOLDED BODY Idemitsu Kosan Co.,Ltd. (JP) 2025-05-21 EP disclosed
US-20250145819-A1 POLYCARBONATE-BASED RESIN COMPOSITION IDEMITSU KOSAN CO.,LTD. (JP) 2025-05-08 US disclosed
US-20250066586-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2025-02-27 US disclosed
EP-4488334-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Engineering-Plastics Corporation (JP) 2025-01-08 EP disclosed
US-20240417520-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2024-12-19 US disclosed
US-20070213452-A1 Light-Diffusing Resin Composition IDEMITSU KOSAN CO., LTD. (JP) 2007-09-13 US disclosed
US-7186734-B2 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION (US) 2007-03-06 US disclosed
US-7186734-B2 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION (US) 2007-03-06 US disclosed
US-7186734-B2 Aryl imidazoles and related compounds as C5a receptor modulators NEUROGEN CORPORATION (US) 2007-03-06 US disclosed
US-20070037906-A1 Polycarbonate resin composition and optical part IDEMITSU KOSAN CO., LTD. (JP) 2007-02-15 US disclosed
EP-1490044-A1 COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS NEUROGEN CORPORATION (US) 2004-12-29 EP disclosed
WO-2003084524-A1 COMBINATION THERAPY FOR THE TREATMENT OF CONDITIONS WITH PATHOGENIC INFLAMMATORY COMPONENTS NEUROGEN CORPORATION (US) 2003-10-16 WO disclosed
US-6548624-B2 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-04-15 US disclosed
US-20020193476-A1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-12-19 US disclosed
US-6476178-B1 Polycarbonate resin composition IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570837-B2 Polycarbonate resin composition and molded article ERCC1, POT1, BMI1 CRHR1 2832/4885C5AR1 2487/4885BCHE 2863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.