Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095853 | 0.95 | CNR2 (0.60) | CNR2MCHR1KDM4ELMNAHTT | |
| SCHEMBL7096588 | 0.95 | CNR2 (0.60) | CNR2MCHR1KDM4ELMNAHTT | |
| SCHEMBL7092601 | 0.93 | CNR2 (0.59) | CNR2MCHR1KDM4ELMNAHTT | |
| SCHEMBL7611913 | 0.93 | CNR2 (0.67) | CNR2MCHR1HTTSMN1; SMN2SERPINE1 | |
| SCHEMBL9307801 | 0.93 | CNR2 (0.67) | CNR2MCHR1HTTSMN1; SMN2SERPINE1 | |
| SCHEMBL7097469 | 0.93 | CNR2 (0.59) | CNR2MCHR1KDM4ELMNAHTT | |
| SCHEMBL2469274 | 0.93 | KDM4E (0.59) | CNR2MCHR1KDM4ELMNAHTT | |
| SCHEMBL7091255 | 0.93 | CNR2 (0.59) | CNR2MCHR1KDM4ELMNAHTT | |
| SCHEMBL7092599 | 0.93 | CNR2 (0.59) | CNR2MCHR1KDM4ELMNAHTT | |
| SCHEMBL7091892 | 0.93 | CNR2 (0.59) | CNR2MCHR1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | claimed |
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107423-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | CNR2 4537/4885MCHR1 4751/4885KDM4E 4453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.