Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096588 | 1.00 | CNR2 (0.60) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7091892 | 0.98 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7092599 | 0.98 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7091255 | 0.98 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7097469 | 0.98 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7092601 | 0.98 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7096609 | 0.98 | CNR2 (0.59) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7092691 | 0.96 | CNR2 (0.57) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL6490141 | 0.95 | CNR2 (0.67) | CNR2HTTLMNASMN1; SMN2SERPINE1 | |
| SCHEMBL7201208 | 0.95 | CNR2 (0.56) | CNR2HTTLMNASMN1; SMN2SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627399-B1 | Using compound of given formula as accelerator | RIKEN (JP) | 2003-09-30 | — | — | US | disclosed |
| US-6605645-B2 | Such as 1,15-di(cyclopropylmethylamino)-8-benzyl-4,8,12-triazapentadecane; carcinostatic action | RIKEN (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030073202-A1 | RNA polymerase transcription promoter and nucleic acid sequencing method | IWATA MASAAKI (JP) | 2003-04-17 | — | — | US | disclosed |
| US-20020067472-A1 | Linear polyamine compounds and polyamine anticancer agents | IWATA MASAAKI (JP) | 2002-06-06 | — | — | US | disclosed |
| US-6319956-B1 | N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. | RIKEN (JP) | 2001-11-20 | — | — | US | disclosed |
| EP-1061130-A1 | RNA POLYMERASE TRANSCRIPTION PROMOTERS AND METHOD FOR DETERMINING BASE SEQUENCE | Riken (JP) | 2000-12-20 | — | — | EP | disclosed |