Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.55 |
| ▸ | PPARA | Q07869 | 14/20 | 0.55 |
| ▸ | PPARG | P37231 | 10/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6489283 | 0.91 | PPARD (0.47) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6491782 | 0.91 | PPARD (0.52) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6487860 | 0.84 | PPARD (0.46) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6491177 | 0.80 | PPARD (0.40) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6502085 | 0.78 | NR1H4 (0.49) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6497809 | 0.76 | MCL1 (0.41) | FFAR1 | |
| SCHEMBL6491350 | 0.76 | MAPT (0.44) | PPARDPPARAPPARG | |
| SCHEMBL5654322 | 0.75 | PPARD (0.81) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6614634 | 0.74 | PPARD (0.85) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6488835 | 0.73 | MCL1 (0.42) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | PPARD 290/4885PPARA 665/4885PPARG 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.