Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19447416 | 0.84 | CSNK2A1 (0.45) | CSNK2A1FFAR4SLC9A1TSPOHTR2A | |
| SCHEMBL16950499 | 0.82 | MAPT (0.53) | CSNK2A1FFAR4SLC9A1TSPOHTR2A | |
| SCHEMBL15539889 | 0.82 | KMT2A (0.46) | CSNK2A1CCR5HTR2ATSHRSLC6A4 | |
| Hydrochloric Acid SCHEMBL15559545 | 0.81 | KMT2A (0.45) | CSNK2A1CCR5HTR2ATSHRHTR2C | |
| SCHEMBL12697235 | 0.80 | NOS3 (0.50) | CSNK2A1NOS3NOS1FFAR4TSHR | |
| SCHEMBL1196055 | 0.79 | KDM4E (0.47) | CCR5SLC6A4KCNH2MEN1LMNA | |
| SCHEMBL20472358 | 0.79 | CSNK2A1 (0.47) | CSNK2A1NOS3NOS1SLC6A4KCNH2 | |
| SCHEMBL12695021 | 0.79 | CSNK2A1 (0.47) | CSNK2A1NOS3NOS1TSHRGAA | |
| SCHEMBL5759267 | 0.78 | FFAR4 (0.44) | CSNK2A1FFAR4TSPOHTR2ATSHR | |
| Hydrochloric Acid SCHEMBL31321966 | 0.78 | KDM4E (0.46) | CCR5SLC6A4KCNH2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171049-A1 | Compounds for the treatment of ischemia | DENINNO MICHAEL P (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1241176-A1 | Purine derivatives for the treatment of ischemia | Pfizer Products Inc. (US) | 2002-09-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171049-A1 | Compounds for the treatment of ischemia | TNNI3, ADRB3, TBXA2R | CSNK2A1 3046/4885NOS3 116/4885NOS1 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.