SCHEMBL6701668

SCHEMBL6701668

CCCCCCCOP(=S)(S)OCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 15/20 0.64
LPAR2 Q9HBW0 13/20 0.64
LPAR1 Q92633 10/20 0.52
LPAR6 P43657 5/20 0.43
LPAR4 Q99677 5/20 0.43
LPAR5 Q9H1C0 5/20 0.43
CYP3A4 P08684 1/20 0.42
LMNA P02545 1/20 0.41
ESR1 P03372 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
CDC25A P30304 1/20 0.41
AGTR1 P30556 1/20 0.41
AKT1 P31749 1/20 0.41
ADRA1A P35348 1/20 0.41
KCNH2 Q12809 1/20 0.41
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26234272 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL9676047 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL5453677 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL5086025 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL649061 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL7948187 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL1262956 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL4436297 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL11025774 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4
SCHEMBL2716235 1.00 LPAR3 (0.64) LPAR3LPAR2LPAR1LPAR6LPAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1737936-B1 HYDRAULIC COMPOSITION CONTAINING A SUBSTANTIALLY NITROGEN FREE DISPERSANT LUBRIZOL CORP (US) 2017-01-25 EP claimed
EP-1227145-B1 Lubricating oil compositions NIPPON MITSUBISHI OIL CORP (JP) 2013-03-13 EP disclosed
US-20040204325-A1 Transmission fluid compositions for automobiles NIPPON OIL CORPORATION 2004-10-14 US disclosed
US-20040192562-A1 Lubricating oil composition NIPPON OIL CORPORATION 2004-09-30 US disclosed
US-6656887-B2 Metal salt or amine salt of thiophosphate or of phosphate are decreased in sulfur content and excellent in the ability to maintain the total base number NIPPON MITSUBISHI OIL CORPORATION (JP) 2003-12-02 US disclosed
US-20020142922-A1 Lubricating oil compositions NIPPON MITSUBISHI OIL CORPORATION 2002-10-03 US disclosed
EP-1227145-A1 Lubricating oil compositions Nippon Mitsubishi Oil Corporation (JP) 2002-07-31 EP disclosed
US-5942470-A OIL SOLUBLE SULFUR CONTAINING PRESSURE AND ANTI-WEAR AGENT, AMINE SALT OF PHOSPHORUS ESTER, SUCCINIMIDE, AND ASHLESS DISPERSANTS ETHYL PETROLEUM ADDITIVES, INC. (US) 1999-08-24 US disclosed
EP-0459656-B1 Lubricant compositions ETHYL PETROLEUM ADDITIVES INC (US) 1995-09-20 EP disclosed
EP-0459656-A1 Lubricant compositions ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-12-04 EP disclosed