SCHEMBL6491291

SCHEMBL6491291

CC1CC2CC(=O)C=CN2C2CCC(C)(Cl)CC12

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.50
SRD5A1 P18405 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6430872 0.79 SRD5A2 (0.46) SRD5A2SRD5A1
SCHEMBL6430847 0.77 SRD5A2 (0.43) SRD5A2SRD5A1
SCHEMBL6432320 0.77 SRD5A2 (0.44) SRD5A2SRD5A1
SCHEMBL6432242 0.62 SRD5A2 (0.45) SRD5A2SRD5A1
SCHEMBL6431481 0.60 SRD5A2 (0.38) SRD5A2SRD5A1
SCHEMBL6431812 0.59 SRD5A2 (0.42) SRD5A2SRD5A1
SCHEMBL6431351 0.59 SRD5A2 (0.40) SRD5A2SRD5A1
SCHEMBL6431337 0.59 SRD5A2 (0.39) SRD5A2SRD5A1
SCHEMBL6431503 0.58 SRD5A2 (0.47) SRD5A2SRD5A1
SCHEMBL6435004 0.58 SRD5A2 (0.47) SRD5A2SRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6962925-B1 Benzo(C)quinolizine derivatives and their use as 5α-reductases inhibitors APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) 2005-11-08 US claimed