Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196591 | 0.92 | ACE (0.52) | ACEDPP8F2FKBP1ADPP4 | |
| SCHEMBL11191259 | 0.89 | ACE (0.55) | ACEDPP8FKBP1ADPP4DPP9 | |
| SCHEMBL11195194 | 0.88 | ACE (0.52) | ACEDPP8FKBP1ADPP4DPP9 | |
| SCHEMBL10882970 | 0.87 | ACE (0.50) | ACEDPP8FKBP1ADPP4DPP9 | |
| SCHEMBL10882819 | 0.86 | ACE (0.51) | ACEDPP8FKBP1ADPP4DPP9 | |
| SCHEMBL3370866 | 0.85 | ACE (0.49) | ACEDPP8F2FKBP1ADPP4 | |
| SCHEMBL11192710 | 0.85 | ACE (0.51) | ACEDPP8FKBP1ADPP4DPP9 | |
| SCHEMBL10881981 | 0.85 | ACE (0.49) | ACEDPP8FKBP1ADPP4DPP9 | |
| SCHEMBL11190870 | 0.85 | ACE (0.49) | ACEDPP8F2FKBP1ADPP4 | |
| SCHEMBL11195321 | 0.85 | ACE (0.50) | ACEDPP8FKBP1ADPP4DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119817-B2 | Process for separating the diastereomers of RSS-and SSS-N- α [1-carboxy-3-phenylpropyl] lysylproline | DEGUSSA-HUELS AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20110077412-A1 | Process for separating the diastereomers of RSS-snd SSS-N- a [1-carboxy -3-Phenylpropyl] lysylproline | DEGUSSA-HUELS AG (DE) | 2011-03-31 | — | — | US | disclosed |