Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491292 | 0.92 | SLC6A2 (0.45) | SLC6A2SLC6A4KLK7POLBALDH1A1 | |
| SCHEMBL6504655 | 0.90 | SLC6A2 (0.39) | SLC6A2SLC6A4KLK7POLBTSHR | |
| SCHEMBL6244320 | 0.89 | SLC6A2 (0.39) | SLC6A2KLK7POLBGAATAAR1 | |
| SCHEMBL6243782 | 0.89 | SLC6A2 (0.39) | SLC6A2SLC6A4KLK7POLBMAPT | |
| SCHEMBL6241609 | 0.89 | SLC6A2 (0.39) | SLC6A2SLC6A4KLK7POLBTAAR1 | |
| SCHEMBL6247507 | 0.89 | PARP1 (0.42) | SLC6A2KLK7TSHRPARP1 | |
| SCHEMBL6502626 | 0.87 | SLC6A2 (0.38) | SLC6A2SLC6A4KLK7POLBTAAR1 | |
| SCHEMBL6494315 | 0.85 | SLC6A2 (0.40) | SLC6A2SLC6A4KLK7POLBGAA | |
| SCHEMBL6246043 | 0.85 | SLC6A2 (0.40) | SLC6A2SLC6A4KLK7POLBMAPT | |
| SCHEMBL6243560 | 0.83 | AAK1 (0.40) | SLC6A2SLC6A4KLK7POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919331-B2 | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-07-19 | — | — | US | disclosed |
| US-20030207868-A1 | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents | BRISTOL-MYERS SQUIBB COMPANY | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207868-A1 | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents | MAVS, ZC3HAV1, EIF2AK2 | SLC6A2 4457/4885SLC6A4 3781/4885KLK7 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.