SCHEMBL649199

SCHEMBL649199

C=C(C)C(=O)OCCC(CCCC)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.57
THRB P10828 1/20 0.46
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
FAAH O00519 1/20 0.33
HPGD P15428 1/20 0.33
PLA2G2C Q5R387 1/20 0.32
DPP4 P27487 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
DPP7 Q9UHL4 1/20 0.32
CYP3A4 P08684 1/20 0.32
ATM Q13315 1/20 0.32
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28294683 0.94 TSHR (0.63) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL650573 0.88 TSHR (0.73) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL11528787 0.83 TSHR (0.61) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL22567351 0.81 TSHR (0.62) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL4384013 0.81 TSHR (0.53) TSHRTHRBCA1FAAH
SCHEMBL16488585 0.80 TSHR (0.49) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL29500356 0.80 TSHR (0.66) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL9243433 0.80 TSHR (0.61) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL10150618 0.80 TSHR (0.66) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL11526952 0.79 TSHR (0.64) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361408-A1 COATING SYSTEM AND COATED ARTICLE SHERWIN WILLIAMS GUANGDONG NEW MAT CO LTD (CN) 2025-11-27 US disclosed
EP-4646467-A1 TWO-COMPONENT COATING COMPOSITION, AND ARTICLE MADE THEREFROM Valspar Coatings (Shanghai) Co. Ltd. (CN) 2025-11-12 EP disclosed
US-12460104-B2 Two-component waterborne polyurethane coating composition and low gloss coating formed therefrom Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) 2025-11-04 US disclosed
WO-2025082420-A1 AQUEOUS EMULSION, METHOD FOR PREPARING THE SAME, COATING COMPOSITION AND ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2025-04-24 WO disclosed
US-12168757-B2 Well defined low molecular weight dispersant polymethacrylates THE LUBRIZOL CORPORATION (US) 2024-12-17 US disclosed
WO-2024146484-A1 TWO-COMPONENT COATING COMPOSITION, AND ARTICLE MADE THEREFROM VALSPAR COATINGS (SHANGHAI) CO. LTD. (CN) 2024-07-11 WO disclosed
EP-4150034-B1 LUBRICATING COMPOSITION FOR AND METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE LUBRIZOL CORP (US) 2024-03-13 EP disclosed
US-20230183595-A1 WELL DEFINED LOW MOLECULAR WEIGHT DISPERSANT POLYMETHACRYLATES THE LUBRIZOL CORPORATION (US) 2023-06-15 US disclosed
CN-115916930-A Lubricating composition for lubricating an internal combustion engine and method of lubricating an internal combustion engine 路博润公司 2023-04-04 CN disclosed
EP-4150034-A1 LUBRICATING COMPOSITION FOR AND METHOD OF LUBRICATING AN INTERNAL COMBUSTION ENGINE The Lubrizol Corporation (US) 2023-03-22 EP disclosed
US-7695813-B2 Core and shell particle for modifying impact resistance of a mouldable poly (meth) acrylate material ROEHM GMBH & CO. KG (DE) 2010-04-13 US disclosed
US-20090105399-A1 TRANSPARENT TPU (THERMOPLASTIC POLYURETHANES)/PMMA (POLYMETHYL (METH) ACRYLATE) BLENDS WITH IMPROVED LOW-TEMPERATURE IMPACT RESISTANCE EVONIK ROEHM GMBH (DE) 2009-04-23 US disclosed
CN-100457799-C Core and shell particle for modifying impact resistance of a mouldable poly(meth)acrylate material ROEHM GMBH (DE) 2009-02-04 CN disclosed
US-20080132627-A1 Impact-Resistant Poly(Meth)Acrylate Moulding Masses With High Thermal Stability ROEHM GMBH (DE) 2008-06-05 US disclosed
CN-100376612-C Method for producing aqueous dispersions ROEHM GMBH (DE) 2008-03-26 CN disclosed
US-20060147714-A1 Core and shell particle for modifying impact resistance of a mouldable poly (meth) acrylate material ROEHM GMBH & CO. KG (DE) 2006-07-06 US disclosed
US-20060052515-A1 Process for producing aqueou dispersions ROEHM GMBH & CO. KG (DE) 2006-03-09 US disclosed
CN-1729219-A Process for preparing aqueous dispersions ROEHM GMBH (DE) 2006-02-01 CN disclosed
CN-1726238-A Core and shell particle for modifying impact resistance of a mouldable poly(meth)acrylate material ROEHM GMBH (DE) 2006-01-25 CN disclosed
CN-1589182-A Method for producing layers ROEHM GMBH (DE) 2005-03-02 CN disclosed