Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | DGKA | P23743 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL650573 | 0.94 | TSHR (0.73) | TSHRTHRBFAAHGPR84FFAR1 | |
| SCHEMBL649199 | 0.94 | TSHR (0.57) | TSHRTHRBFAAHPOLBAPEX1 | |
| SCHEMBL4384013 | 0.84 | TSHR (0.53) | TSHRTHRBFAAHGPR84FFAR1 | |
| SCHEMBL11526952 | 0.83 | TSHR (0.64) | TSHRTHRBFAAHGPR84ZDHHC7 | |
| SCHEMBL866131 | 0.81 | TSHR (0.77) | TSHRTHRBFAAHZDHHC7POLB | |
| SCHEMBL9658227 | 0.81 | TSHR (0.77) | TSHRTHRBFAAHZDHHC7POLB | |
| SCHEMBL651728 | 0.81 | TSHR (0.77) | TSHRTHRBFAAHZDHHC7POLB | |
| SCHEMBL2912477 | 0.81 | TSHR (0.77) | TSHRTHRBFAAHZDHHC7POLB | |
| SCHEMBL7736289 | 0.81 | TSHR (0.77) | TSHRTHRBFAAHZDHHC7POLB | |
| SCHEMBL651327 | 0.81 | TSHR (0.77) | TSHRTHRBFAAHZDHHC7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109880671-A | A kind of high viscosity index improver and its preparation method and application | 一汽解放汽车有限公司 | 2019-06-14 | — | — | CN | disclosed |