Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 5/20 | 0.53 |
| ▸ | PDE5A | O76074 | 12/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 1/20 | 0.40 |
| ▸ | PDE8A | O60658 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492024 | 1.00 | TERT (0.53) | TERTPDE5APDE3BPDE3AHDAC1 | |
| SCHEMBL29897708 | 1.00 | TERT (0.53) | TERTPDE5APDE3BPDE3AHDAC1 | |
| SCHEMBL6730079 | 0.93 | TERT (0.44) | TERTPDE5APDE3BPDE3AHDAC1 | |
| SCHEMBL4565717 | 0.88 | TERT (0.56) | TERTPDE5APDE3BPDE3AHDAC1 | |
| SCHEMBL8125815 | 0.84 | TERT (0.62) | TERTPDE5APDE3BPDE3AKMT2A | |
| SCHEMBL25925357 | 0.83 | PDE5A (0.46) | PDE5APDE3BPDE3AHDAC1HDAC6 | |
| SCHEMBL7006683 | 0.81 | TERT (0.58) | TERTPDE5AHDAC1HDAC6HDAC2 | |
| SCHEMBL7253729 | 0.81 | TERT (0.58) | TERTPDE5AHDAC1HDAC6HDAC2 | |
| SCHEMBL6207835 | 0.80 | TERT (0.65) | TERTPDE5APDE3BPDE3ACA12 | |
| SCHEMBL1705329 | 0.78 | TERT (0.61) | TERTPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400522-B1 | COMPOUNDS FOR TREATING IMPOTENCE | GUANGZHOU YOUCARE BIOPHARMACEATICS CO LTD (CN) | 2014-08-06 | — | — | EP | claimed |
| US-6960592-B2 | 1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one compound for the treatment of impotence | LIU BAOSHUN | 2005-11-01 | — | — | US | claimed |
| US-20040152709-A1 | New compound for the treatment of impotence | LIU BAOSHUN (CN) | 2004-08-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152709-A1 | New compound for the treatment of impotence | PDE3B, PDE3A, PDE5A | TERT 2811/4885PDE5A 3/4885PDE3B 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.