Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494500 | 0.89 | PARP1 (0.45) | PARP1PARP15PARP10LMNAPOLB | |
| SCHEMBL6489189 | 0.89 | HSD17B10 (0.46) | HSD17B10LMNAUBE2MDCUN1D1POLB | |
| SCHEMBL6493472 | 0.87 | PARP1 (0.44) | PARP1PARP15PARP10HSD17B10POLB | |
| SCHEMBL6490780 | 0.87 | NPSR1 (0.48) | HSD17B10LMNAUBE2MDCUN1D1POLB | |
| SCHEMBL6480181 | 0.87 | NPSR1 (0.51) | HSD17B10LMNAUBE2MDCUN1D1POLB | |
| SCHEMBL6480935 | 0.86 | NPSR1 (0.50) | HSD17B10LMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL6480758 | 0.85 | PARP1 (0.42) | PARP1PARP15PARP10HSD17B10LMNA | |
| SCHEMBL6480301 | 0.83 | PARP1 (0.44) | PARP1PARP15PARP10UBE2MDCUN1D1 | |
| SCHEMBL6487994 | 0.79 | MEN1 (0.46) | LMNAUBE2MDCUN1D1MAPTNPSR1 | |
| SCHEMBL6489116 | 0.79 | HSD17B10 (0.44) | HSD17B10LMNAMAPTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | IDO1, IDO2, HAVCR2 | PARP1 3678/4885PARP15 2460/4885PARP10 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.