Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490688 | 0.90 | MGLL (0.44) | NPC1RAB9ASMN1; SMN2MGLLGAA | |
| SCHEMBL6480758 | 0.89 | PARP1 (0.42) | PARP1PARP15PARP10SMN1; SMN2MAPT | |
| SCHEMBL6492402 | 0.88 | NPSR1 (0.46) | NPC1RAB9ASMN1; SMN2MGLLMALT1 | |
| SCHEMBL6489974 | 0.88 | JAK2 (0.43) | NPC1RAB9ASMN1; SMN2MGLLGAA | |
| SCHEMBL6492666 | 0.87 | NPSR1 (0.45) | NPC1RAB9ASMN1; SMN2MGLLMALT1 | |
| SCHEMBL6492249 | 0.87 | PARP1 (0.48) | PARP1PARP15PARP10NPC1RAB9A | |
| SCHEMBL6489116 | 0.84 | HSD17B10 (0.44) | SMN1; SMN2MGLLGAAMAPTMAOB | |
| SCHEMBL6494500 | 0.84 | PARP1 (0.45) | PARP1PARP15PARP10MALT1POLB | |
| SCHEMBL6487994 | 0.83 | MEN1 (0.46) | SMN1; SMN2MGLLMAPTMALT1 | |
| SCHEMBL6480722 | 0.82 | NPSR1 (0.49) | SMN1; SMN2MAOBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | RIGEL PHARMACEUTICALS, INC. (US) | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215614-A1 | Substituted indoles and their use as hcv inhibitors | IDO1, IDO2, HAVCR2 | PARP1 3678/4885PARP15 2460/4885PARP10 2475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.