Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 4/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.50 |
| ▸ | TERT | O14746 | 4/20 | 0.49 |
| ▸ | PKLR | P30613 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6503595 | 0.77 | TTR (0.44) | BCL2MCL1TERTMAPTMEN1 | |
| SCHEMBL6169603 | 0.76 | MCL1 (0.61) | BCL2MCL1PKLRMAPTMAOA | |
| SCHEMBL11809264 | 0.73 | MCL1 (0.65) | BCL2MCL1PKLRMAPTMAOA | |
| SCHEMBL2769983 | 0.69 | BCL2 (1.00) | BCL2MCL1TERTPKLRMAPT | |
| SCHEMBL2023599 | 0.69 | KMT2A (0.53) | BCL2MCL1MAPTMEN1KMT2A | |
| SCHEMBL555230 | 0.67 | BCL2 (1.00) | BCL2MCL1PKLRMAPTMAOA | |
| SCHEMBL29384381 | 0.67 | BCL2 (1.00) | BCL2MCL1PKLRMAPTMAOA | |
| Xanthopurpurin SCHEMBL1426707 | 0.67 | BCL2 (1.00) | BCL2MCL1PKLRMAPTMAOA | |
| Xanthopurpurin SCHEMBL29407313 | 0.67 | BCL2 (1.00) | BCL2MCL1PKLRMAPTMAOA | |
| SCHEMBL29388375 | 0.67 | BCL2 (1.00) | BCL2MCL1PKLRMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881850-B2 | Heterocyclically annellated indenochromene derivatives | RODENSTOCK GMBH (DE) | 2005-04-19 | — | — | US | disclosed |
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | OPTISCHE WERKE G. RODENSTOCK | 2004-05-13 | — | — | US | disclosed |
| US-6660727-B1 | Photochromic heterocyclically anellated indenochromene compounds | RODENSTOCK GMBH (DE) | 2003-12-09 | — | — | US | disclosed |
| EP-1144416-A1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | Optische Werke G. Rodenstock (DE) | 2001-10-17 | — | — | EP | disclosed |
| WO-2001034609-A1 | HETEROCYCLICALLY ANELLATED INDENOCHROMENE DERIVATIVES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-05-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040092743-A1 | Heterocyclically annellated indenochromene derivatives | ALDH1A2, INF2, CYP1B1 | BCL2 3742/4885MCL1 3858/4885TERT 985/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.