Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | INSR | P06213 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668458 | 0.74 | USP8 (0.36) | USP8IDO1SMN1; SMN2GSK3BMEN1 | |
| SCHEMBL6668456 | 0.74 | USP8 (0.36) | USP8IDO1SMN1; SMN2GSK3BMEN1 | |
| SCHEMBL16144849 | 0.71 | USP8 (0.48) | USP8SMN1; SMN2GSK3BMEN1KMT2A | |
| SCHEMBL29606493 | 0.66 | CYP1A2 (0.50) | CYP1A2SMN1; SMN2GSK3BMEN1KMT2A | |
| SCHEMBL1554278 | 0.66 | CYP1A2 (0.50) | CYP1A2SMN1; SMN2GSK3BMEN1KMT2A | |
| SCHEMBL7981109 | 0.66 | SLC6A15 (0.35) | USP8IDO1MEN1KMT2AALDH1A1 | |
| SCHEMBL5893999 | 0.63 | MAPT (0.47) | CYP1A2SMN1; SMN2GSK3BMEN1KMT2A | |
| SCHEMBL6246167 | 0.61 | ALDH1A1 (0.43) | IDO1CYP1A2SMN1; SMN2NTRK1MAPT | |
| SCHEMBL6246169 | 0.61 | ALDH1A1 (0.43) | IDO1CYP1A2SMN1; SMN2NTRK1MAPT | |
| SCHEMBL10625937 | 0.61 | LRRK2 (0.53) | IDO1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844342-B2 | Heterocyclic substituted 2-methyl-benzimidazole antiviral agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-01-18 | — | — | US | disclosed |