⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945055 | 0.98 | CYP3A4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL310787 | 0.98 | CYP3A4 (0.42) | — | |
| Hydrochloric Acid SCHEMBL311521 | 0.98 | CYP3A4 (0.42) | — | |
| SCHEMBL7500298 | 0.98 | CYP3A4 (0.42) | — | |
| SCHEMBL15880175 | 0.92 | CYP3A4 (0.39) | — | |
| Formaldoxime SCHEMBL4910460 | 0.89 | CYP3A4 (0.37) | — | |
| Urea SCHEMBL15380857 | 0.89 | ALDH1A1 (0.38) | — | |
| Hexane SCHEMBL28298905 | 0.87 | CYP2D6 (0.46) | — | |
| Acetamide SCHEMBL9934071 | 0.86 | CCNC (0.37) | — | |
| SCHEMBL28294876 | 0.80 | HRH3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4453 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478295-B1 | SYNTHESIS OF N-(HETEROARYL)-PYRROLO[3,2-D]PYRIMIDIN-2-AMINES | PHARMACOSMOS HOLDING AS (DK) | 2026-05-27 | — | — | EP | claimed |
| CN-122036736-A | Pyrrolo [2,3-d ] pyrimidine derivative, synthetic method and application | 云南大学 | 2026-05-15 | — | — | CN | claimed |
| EP-4363043-B1 | COMPOSITIONS FOR USE IN METHODS FOR INCREASING CANCER CELL SENSITIVITY TO ALTERNATING ELECTRIC FIELDS | NOVOCURE GMBH (CH) | 2026-04-22 | — | — | EP | claimed |
| WO-2025149628-A1 | PIPERIDINE DERIVATIVES AS INHIBITORS OF NICOTINAMIDE N-METHYL TRANSFERASE | ASTRAZENECA AB (SE) | 2025-07-17 | — | — | WO | claimed |
| CN-119977970-A | Luxolitic preparation method of nylon | 雅本(绍兴)药业有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-117777136-B | 1, 3-Disubstituted tetrahydropyrrole derivative and preparation method and application thereof | 沈阳药科大学 | 2025-04-29 | — | — | CN | claimed |
| WO-2025082069-A1 | COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN | 中国海洋大学 | 2025-04-24 | — | — | WO | claimed |
| US-20250129429-A1 | GENE FUSIONS IN SARCOMA | FOUNDATION MEDICINE, INC. (US) | 2025-04-24 | — | — | US | claimed |
| CN-119841843-A | Compound combined with CRBN protein and degradation agent of CRBN protein | 中国海洋大学 | 2025-04-18 | — | — | CN | claimed |
| CN-119613409-A | Pyrrolo [2,3-d ] pyrimidine derivatives and their use in the preparation of anti-inflammatory agents | 浙江工业大学 | 2025-03-14 | — | — | CN | claimed |
| EP-0673376-A1 | NOVEL BICYCLIC PYRIMIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS. | ADIR (FR) | 1995-09-27 | — | — | EP | claimed |
| US-5349064-A | Production of pyrrolopyrimidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-09-20 | — | — | US | claimed |
| WO-1994013668-A1 | NOVEL BICYCLIC PYRIMIDINE COMPOUNDS, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS | ADIR ET COMPAGNIE (FR) | 1994-06-23 | — | — | WO | claimed |
| EP-0549886-A1 | Process for the preparation of pyrrolo[2,3-d]pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1993-07-07 | — | — | EP | claimed |
| EP-0514540-A1 | PYRROLO 2,3-d]PYRIMIDINE DERIVATIVE, PROCESS FOR PREPARING THE SAME, AND PHARMACEUTICAL PREPARATION COMPRISING THE DERIVATIVE AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1992-11-25 | — | — | EP | claimed |
| WO-1992012718-A1 | ADENOSINE KINASE INHIBITORS | GENSIA, INC. (US) | 1992-08-06 | — | — | WO | claimed |
| EP-0496617-A1 | Adenosine kinase inhibitors | GENSIA, INC. (US) | 1992-07-29 | — | — | EP | claimed |
| CN-1048705-A | Process for preparing pyrrolopyrimidines and intermediates thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-01-23 | — | — | CN | claimed |
| EP-0402903-A1 | Production of pyrrolopyrimidines and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1990-12-19 | — | — | EP | claimed |
| US-4028184-A | CULTURING CORYNEBACTERIUM, ARTHROBACTER, MICROBACTERIUM | KIKKOMAN SHOYU CO., LTD. (JA) | 1977-06-07 | — | — | US | claimed |