Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13204668 | 1.00 | TSHR (0.69) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL1496759 | 1.00 | TSHR (0.69) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL14173945 | 0.90 | TSHR (0.58) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL6228324 | 0.89 | AR (0.61) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL14173741 | 0.84 | TSHR (0.56) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL1496665 | 0.84 | POLB (0.57) | TSHRMAPK1CYP2C9LMNAPOLB | |
| SCHEMBL14934283 | 0.84 | TSHR (0.62) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL16174419 | 0.84 | TSHR (0.62) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL1496690 | 0.84 | TSHR (0.62) | TSHRMAPK1CYP2C9LMNAAGTR1 | |
| SCHEMBL8811629 | 0.83 | AR (0.56) | TSHRMAPK1LMNAAGTR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056549-A1 | WATER-SOLUBLE ETOPOSIDE ANALOGS AND METHODS OF USE THEREOF | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2005-06-23 | — | — | WO | claimed |
| WO-2022253331-A1 | INTERMEDIATE FOR PREPARING PHOSPHATIDYLETHANOLAMINE AND PREPARATION METHOD OF INTERMEDIATE | 上海弼领生物技术有限公司 | 2022-12-08 | — | — | WO | disclosed |
| WO-2005003140-A1 | 4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-01-13 | — | — | WO | disclosed |
| US-20050004161-A1 | 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | AGOURON PHARMACEUTICALS, INC. | 2005-01-06 | — | — | US | disclosed |
| US-6573246-B1 | Anticancer agents | THE LIPOSOME COMPANY, INC. | 2003-06-03 | — | — | US | disclosed |
| US-6153736-A | ANTICANCER AGENTS | THE LIPOSOME COMPANY, INC. (US) | 2000-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004161-A1 | 4-oxo-4,7-dihydrothieno[2,3-b]pyridine-5-carboxamides as antiviral agents | ZC3HAV1, IRF3, BRD4 | TSHR 3008/4885MAPK1 3670/4885CYP2C9 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.