Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16174419 | 1.00 | TSHR (0.62) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL14934283 | 1.00 | TSHR (0.62) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL14173941 | 0.90 | TSHR (0.53) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL14173722 | 0.90 | TSHR (0.53) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL14189198 | 0.90 | USP2 (0.68) | TSHRUSP2CYP1A2MAPTLMNA | |
| SCHEMBL6228324 | 0.89 | AR (0.61) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL14173758 | 0.86 | TSHR (0.49) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL14174230 | 0.86 | TSHR (0.49) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL12795506 | 0.86 | TSHR (0.49) | TSHRUSP2ARMAPK1CYP1A2 | |
| SCHEMBL14173956 | 0.86 | TSHR (0.49) | TSHRUSP2ARMAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110980655-A | Method for recovering sulfur from byproduct gypsum of sulfur-containing wastewater | 西南科技大学 | 2020-04-10 | — | — | CN | claimed |
| CN-104788902-A | Inorganic/organic hybrid epoxy resin reinforcing agent | UNIV JIANGNAN | 2015-07-22 | — | — | CN | claimed |
| EP-2051962-A1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2009-04-29 | — | — | EP | claimed |
| WO-2008017989-A1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-02-14 | — | — | WO | claimed |
| EP-0149652-B1 | METHOD OF PREPARING MOULDING COMPOSITIONS | POLYMER TECTONICS LIMITED (GB) | 1989-11-08 | — | — | EP | claimed |
| CN-113372568-B | Preparation method of neodymium-based or holmium-based chiral metal-organic porous crystalline material, prepared material and application thereof | 合肥工业大学 | 2022-07-22 | — | — | CN | disclosed |
| CN-113372568-A | Preparation method of neodymium-based or holmium-based chiral metal-organic porous crystalline material, prepared material and application thereof | 合肥工业大学 | 2021-09-10 | — | — | CN | disclosed |
| EP-3501488-B1 | AQUEOUS SILICONE POLYMER COMPOSITIONS | MOMENTIVE PERFORMANCE MAT GMBH (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-10947383-B2 | Aqueous silicone polymer compositions | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2021-03-16 | — | — | US | disclosed |
| US-20190194457-A1 | AQUEOUS SILICONE POLYMER COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2019-06-27 | — | — | US | disclosed |
| EP-3501488-A1 | AQUEOUS SILICONE POLYMER COMPOSITIONS | Momentive Performance Materials GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |
| CN-104768991-B | New impact modifier for epoxy adhesive | SIKA技术股份公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-1126441-A | Amplification of vitamin B12 absorption System Using polymers | BIOTECH AUSTRALIA PTY LTD (AU) | 1996-07-10 | — | — | CN | disclosed |
| US-5276098-A | Thermoplastic saturated norbornene group polymer composition | NIPPON ZEON CO., LTD. (JP) | 1994-01-04 | — | — | US | disclosed |
| EP-0498564-A2 | Thermoplastic saturated norbornene group polymer composition | NIPPON ZEON CO., LTD. (JP) | 1992-08-12 | — | — | EP | disclosed |
| EP-0023135-A1 | Phenolic resin particles, process for their production and friction elements containing them | OCCIDENTAL CHEMICAL CORPORATION (US) | 1981-01-28 | — | — | EP | disclosed |
| US-4209447-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1980-06-24 | — | — | US | disclosed |
| US-4139540-A | FUNGICIDE, BACTERICIDE INTERMEDIATE | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-02-13 | — | — | US | disclosed |
| US-4115509-A | INJECTION MOLDING, AMINO RESINS, CURING | BRITISH INDUSTRIAL PLASTICS LTD. (GB) | 1978-09-19 | — | — | US | disclosed |
| US-3936470-A | FUNGICIDES, BACTERICIDES | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10947383-B2 | Aqueous silicone polymer compositions | CUTA, IL6, SHC1 | TSHR 4552/4885USP2 1335/4885AR 3010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.