Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | GAA | P10253 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 7/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | HPGD | P15428 | 7/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.73 |
| ▸ | NPC1 | O15118 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.73 |
| ▸ | TP53 | P04637 | 4/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.73 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.73 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.73 |
| ▸ | GLA | P06280 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494910 | 0.84 | MEN1 (1.00) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6483416 | 0.78 | ALDH1A1 (0.79) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6482060 | 0.77 | RPS6KA3 (0.64) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6483072 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6483081 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6493950 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6483421 | 0.75 | MEN1 (1.00) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL5354818 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL6507007 | 0.70 | ALDH1A1 (0.57) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL28257886 | 0.70 | RPS6KA3 (0.73) | ALDH1A1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | BF RESEARCH INSTITUTE (JP) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050260126-A1 | Diagnostic probes and remedies for diseases with accumulation of prion protein, and stains for prion protein | PRNP, PRPH, PCNP | ALDH1A1 1577/4885MAPT 7/4885GAA 381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.