Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.62 |
| ▸ | PPARD | Q03181 | 17/20 | 0.62 |
| ▸ | PPARG | P37231 | 15/20 | 0.62 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.51 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.51 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.51 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.51 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494551 | 0.94 | PPARA (0.64) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6495032 | 0.94 | PPARA (0.62) | PPARAPPARDPPARG | |
| SCHEMBL6060693 | 0.89 | PPARA (0.75) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6060697 | 0.89 | PPARA (0.75) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6494291 | 0.89 | PPARA (0.53) | PPARAPPARDPPARG | |
| SCHEMBL6495864 | 0.87 | PPARA (0.53) | PPARAPPARDPPARG | |
| SCHEMBL6502352 | 0.86 | PPARA (0.79) | PPARAPPARDPPARG | |
| SCHEMBL6502380 | 0.83 | PPARA (0.69) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6503654 | 0.83 | ALDH1A1 (0.57) | PPARAPPARDPPARG | |
| SCHEMBL6498633 | 0.82 | PPARA (0.86) | PPARAPPARDPPARGPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |