Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28639229 | 0.89 | PPARG (0.63) | CYP4F2CYP4A11PPARAPPARGDRD2 | |
| SCHEMBL5355607 | 0.87 | MRGPRX4 (0.51) | PPARAPPARGMRGPRX4ALOX5CFD | |
| SCHEMBL491276 | 0.85 | CYP4F2 (0.59) | CYP4F2CYP4A11DRD2LMNASMN1; SMN2 | |
| SCHEMBL4450867 | 0.84 | CYP4F2 (0.55) | CYP4F2CYP4A11DRD2ALOX5LMNA | |
| SCHEMBL8984891 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11DRD2ALOX5APP | |
| SCHEMBL2632416 | 0.84 | CYP4F2 (0.58) | CYP4F2CYP4A11DRD2ALOX5LMNA | |
| SCHEMBL4458645 | 0.83 | CYP3A4 (0.50) | CYP4F2CYP4A11PPARAPPARGALOX5 | |
| SCHEMBL491225 | 0.83 | CYP19A1 (0.60) | CYP4F2CYP4A11ALOX5APPLMNA | |
| SCHEMBL2432179 | 0.83 | CYP4F2 (0.56) | CYP4F2CYP4A11DRD2ALOX5LMNA | |
| SCHEMBL24515574 | 0.82 | MTNR1A (0.48) | PPARAPPARGMRGPRX4ALOX5APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1228327-C | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2005-11-23 | — | — | CN | disclosed |
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| CN-1377336-A | Carboxylic acid derivatives and drugs containing the same | EISAI CO LTD (JP) | 2002-10-30 | — | — | CN | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |