⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3648373 | 0.80 | — | — | |
| SCHEMBL22323276 | 0.78 | — | — | |
| SCHEMBL4067739 | 0.73 | — | — | |
| SCHEMBL25301950 | 0.70 | MAPK1 (0.34) | — | |
| SCHEMBL17228790 | 0.67 | ABAT (0.35) | — | |
| SCHEMBL6422017 | 0.66 | — | — | |
| SCHEMBL6267384 | 0.64 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL7495038 | 0.64 | — | — | |
| SCHEMBL7417349 | 0.64 | TSHR (0.46) | — | |
| SCHEMBL16587928 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123563-A1 | ENGINEERED POLYPEPTIDES THAT EXHIBIT INCREASED CATALYTIC EFFICIENCY FOR UNNATURAL COFACTORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-06-18 | — | — | WO | claimed |
| CN-105339350-B | Dihydropyridone MGAT2 inhibitor | 百时美施贵宝公司 | 2018-05-25 | — | — | CN | claimed |
| CN-102060857-A | Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PHARMACIA ITALIA SPA | 2011-05-18 | — | — | CN | claimed |
| CN-1447810-A | Bicyclic pyrazoles with kinase inhibitor activity, process for their preparation and pharmaceutical compositions containing them | PHARMACIA ITALIA SPA (IT) | 2003-10-08 | — | — | CN | claimed |
| EP-0083378-A1 | Tetrahydronicotinamide derivatives, a process for producing the same and a pharmaceutical composition comprising the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-07-13 | — | — | EP | claimed |
| US-4361572-A | Tetrahydronicotinamide derivative, pharmaceutical compositions and use | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-11-30 | — | — | US | claimed |
| EP-4466266-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | Transneural Therapeutics, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| WO-2024048778-A1 | ARYLTETRAHYDROPYRIDINE COMPOUND AND PEST CONTROL AGENT | 日産化学株式会社 | 2024-03-07 | — | — | WO | disclosed |
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |
| CN-105793239-B | Ultraviolet absorption compound, its composition and application thereof | 珊瑚防晒私人有限公司 | 2019-11-05 | — | — | CN | disclosed |
| CN-106458897-A | Process for producing heterocyclic compound | 武田药品工业株式会社 | 2017-02-22 | — | — | CN | disclosed |
| US-8980907-B2 | Dendrimer conjugates | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2015-03-17 | — | — | US | disclosed |
| US-8889635-B2 | Dendrimer conjugates | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2014-11-18 | — | — | US | disclosed |
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| CN-102060857-A | Bicyclo-pyrazoles active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them | PHARMACIA ITALIA SPA | 2011-05-18 | — | — | CN | disclosed |
| US-20100160299-A1 | DENDRIMER CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010039861-A2 | DENDRIMER CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-04-08 | — | — | WO | disclosed |
| CN-1447810-A | Bicyclic pyrazoles with kinase inhibitor activity, process for their preparation and pharmaceutical compositions containing them | PHARMACIA ITALIA SPA (IT) | 2003-10-08 | — | — | CN | disclosed |
| EP-0083378-A1 | Tetrahydronicotinamide derivatives, a process for producing the same and a pharmaceutical composition comprising the same | Chugai Seiyaku Kabushiki Kaisha (JP) | 1983-07-13 | — | — | EP | disclosed |
| US-4361572-A | Tetrahydronicotinamide derivative, pharmaceutical compositions and use | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-11-30 | — | — | US | disclosed |