Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381953 | 0.83 | HRH3 (0.35) | MAPK1HRH3 | |
| SCHEMBL27548955 | 0.80 | CHRNB2 (0.44) | — | |
| SCHEMBL3893969 | 0.79 | MAPK1 (0.41) | MAPK1HRH3 | |
| Ammonia Solution, Strong SCHEMBL27979051 | 0.77 | MAPK1 (0.40) | MAPK1HRH3 | |
| SCHEMBL9766286 | 0.77 | — | — | |
| SCHEMBL6220124 | 0.76 | MAPT (0.38) | — | |
| SCHEMBL409182 | 0.73 | CHRNB2 (0.42) | MAPK1HRH3 | |
| SCHEMBL29202537 | 0.71 | MIF (0.42) | MAPK1HRH3 | |
| SCHEMBL4757869 | 0.71 | MIF (0.42) | MAPK1HRH3 | |
| SCHEMBL27669362 | 0.71 | MAPK1 (0.36) | MAPK1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125121-A1 | TRICYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2023-07-06 | — | — | WO | disclosed |
| CN-109715630-A | β -lactamase inhibitor compounds | 恩塔西斯治疗有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-103237800-B | Amide derivatives and use thereof | MITSUBISHI TANABE PHARMA CORP. (JP) | 2015-10-21 | — | — | CN | disclosed |