SCHEMBL6495088

SCHEMBL6495088

COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(-n4ccnc4CN)cc2)CC3)cc1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.67
F2 P00734 3/20 0.66
SLC29A1 Q99808 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6492417 0.92 F10 (0.68) F10F2SLC29A1
SCHEMBL6503878 0.91 F10 (0.63) F10F2SLC29A1
SCHEMBL6786084 0.91 F10 (0.67) F10F2SLC29A1
SCHEMBL6502111 0.90 F10 (0.62) F10F2SLC29A1
SCHEMBL6493754 0.89 F10 (0.67) F10F2SLC29A1
SCHEMBL8357512 0.89 F10 (0.64) F10F2SLC29A1
SCHEMBL6495390 0.89 F10 (0.60) F10F2SLC29A1
SCHEMBL6494044 0.89 F10 (0.63) F10F2SLC29A1
SCHEMBL6494981 0.89 F10 (0.60) F10F2SLC29A1
SCHEMBL6782845 0.89 F10 (0.68) F10F2SLC29A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6949550-B2 Substituted amino methyl factor Xa inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2005-09-27 US disclosed
US-20030212054-A1 Substituted amino methyl factor Xa inhibitors BRISTOL-MYERS SQUIBB COMPANY 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030212054-A1 Substituted amino methyl factor Xa inhibitors F11, F10, F9 F10 2/4885F2 12/4885SLC29A1 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.