Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 5/20 | 0.42 |
| ▸ | CNR2 | P34972 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495108 | 1.00 | TSHR (0.45) | TSHRMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL6495106 | 1.00 | TSHR (0.45) | TSHRMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL6481214 | 0.78 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2HPGDGAAP2RX1 | |
| SCHEMBL6481209 | 0.78 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2HPGDGAAP2RX1 | |
| SCHEMBL6481211 | 0.78 | SMN1; SMN2 (0.46) | TSHRSMN1; SMN2HPGDGAAP2RX1 | |
| SCHEMBL10718544 | 0.77 | GAA (0.52) | TSHRSMN1; SMN2HPGDGAAP2RX1 | |
| SCHEMBL11103830 | 0.76 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2HPGDGAAP2RX1 | |
| SCHEMBL11033360 | 0.76 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2HPGDGAAP2RX1 | |
| SCHEMBL11103826 | 0.76 | SMN1; SMN2 (0.44) | TSHRSMN1; SMN2HPGDGAAP2RX1 | |
| SCHEMBL13890643 | 0.73 | TSHR (0.48) | TSHRMEN1KMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032858-A1 | Novel heterocyclic compound and anti-inflamatory agent | NIPPON SODA CO., LTD. (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1435353-A1 | NOVEL HETEROCYCLIC COMPOUND AND ANTI-INFLAMMATORY AGENT | NIPPON SODA CO., LTD. (JP) | 2004-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032858-A1 | Novel heterocyclic compound and anti-inflamatory agent | TLR5, IRF3, IL4 | TSHR 4257/4885MEN1 3730/4885KMT2A 3642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.