⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7379082 | 0.98 | ALOX5 (0.40) | — | |
| SCHEMBL7196351 | 0.78 | — | — | |
| SCHEMBL11325649 | 0.78 | — | — | |
| SCHEMBL9274944 | 0.78 | ALOX5 (0.37) | — | |
| SCHEMBL963358 | 0.77 | ALOX5 (0.39) | — | |
| SCHEMBL7596019 | 0.77 | ALOX5 (0.43) | — | |
| Hydrochloric Acid SCHEMBL10821328 | 0.77 | ALOX5 (0.40) | — | |
| SCHEMBL6997313 | 0.74 | — | — | |
| SCHEMBL5582105 | 0.74 | — | — | |
| SCHEMBL9442383 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7089946-A | — | — | None | — | — | JP | disclosed |
| US-6936606-B2 | Cyanoamido-containing heterocyclic compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-08-30 | — | — | US | disclosed |
| EP-1434769-A2 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-07-07 | — | — | EP | disclosed |
| US-20040063679-A1 | Compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. | 2004-04-01 | — | — | US | disclosed |
| WO-2003029200-A2 | COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-04-10 | — | — | WO | disclosed |
| EP-1157003-A1 | ACYLATED AMINOACETONITRILES AS CYSTEINE PROTEASE INHIBITORS | AstraZeneca AB (SE) | 2001-11-28 | — | — | EP | disclosed |
| EP-1155011-A1 | DI- AND TRIPEPTIDE NITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND CATHEPSIN S | AstraZeneca AB (SE) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000049008-A1 | DI- AND TRIPEPTIDE NITRILE DERIVATIVES AS INHIBITORS OF CATHEPSIN L AND CATHEPSIN S | ASTRAZENECA AB (SE) | 2000-08-24 | — | — | WO | disclosed |
| WO-2000048992-A1 | ACYLATED AMINOACETONITRILES AS CYSTEINE PROTEASE INHIBITORS | ASTRAZENECA AB (SE) | 2000-08-24 | — | — | WO | disclosed |
| EP-0639574-B1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD (KR) | 1998-06-10 | — | — | EP | disclosed |
| US-5426225-A | Chemical intermediate of 2-perfluoroalkyl-3-oxazolin-5-one | AMERICAN CYANAMID COMPANY (US) | 1995-06-20 | — | — | US | disclosed |
| JP-H0789946-A | NOVEL 2-AMINOTHIAZOLECARBOXAMIDE DERIVATIVE, ITS PRODUCTION AND ANTIBACTERIAL AGENT FOR PHYTOPATHOGENIC ORGANISMS | LUCKY CO LTD | 1995-04-04 | — | — | JP | disclosed |
| EP-0639574-A1 | 2-aminothiazolecarboxamide derivatives, processes for their preparation and their use for controlling phytopathogenic organisms | LUCKY LTD. (KR) | 1995-02-22 | — | — | EP | disclosed |
| WO-1994027996-A1 | 1,2,5-THIADIAZOLE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1994-12-08 | — | — | WO | disclosed |
| US-5332825-A | Silyl blocking agent | EASTMAN KODAK COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| US-4804762-A | FUNGICIDES, BACTERICIDES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1989-02-14 | — | — | US | disclosed |
| CN-87104160-A | The N-cyanoalkylisonicotinderivatives derivatives | — | 1988-01-06 | — | — | CN | disclosed |
| EP-0246507-A1 | N-cyanoalkylisonicotinamide derivatives | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4128723-A | BACTERICIDE | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4096329-A | BACTERICIDES | E. R. SQUIBB & SONS, INC. (US) | 1978-06-20 | — | — | US | disclosed |