Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK1 | Q8TE04 | 2/20 | 0.31 |
| ▸ | PANK3 | Q9H999 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101186 | 0.83 | GRM4 (0.34) | KDM4EPDE2A | |
| SCHEMBL4764022 | 0.76 | AKT1 (0.30) | KDM4E | |
| SCHEMBL5781405 | 0.76 | KDM4E (0.33) | KDM4EPDE2A | |
| SCHEMBL4767783 | 0.73 | DPP4 (0.33) | PDE2A | |
| SCHEMBL4768051 | 0.73 | GABRG2 (0.30) | — | |
| SCHEMBL4762748 | 0.73 | PDE2A (0.32) | PDE2A | |
| SCHEMBL6099730 | 0.71 | CYP11B1 (0.33) | KDM4E | |
| SCHEMBL4762545 | 0.69 | PDE2A (0.31) | PDE2A | |
| SCHEMBL6099972 | 0.69 | BACE1 (0.37) | KDM4E | |
| SCHEMBL4769591 | 0.69 | KDM4E (0.32) | KDM4EPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6936617-B2 | Heteroaryl substituted fused bicyclic heteroaryl compound as GABAA receptor ligands | NEUROGEN CORPORATION (US) | 2005-08-30 | — | — | US | disclosed |