SCHEMBL649658

SCHEMBL649658

Nc1ccc(Oc2ccccc2Oc2ccc(N)cc2C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.52
GAA P10253 2/20 0.52
GLA P06280 1/20 0.52
POLB P06746 1/20 0.52
MAOA P21397 1/20 0.41
MAPK1 P28482 1/20 0.38
AR P10275 6/20 0.37
CYP3A4 P08684 2/20 0.37
ESRRA P11474 1/20 0.37
KIF11 P52732 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
SRC P12931 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8766226 1.00 TSHR (0.52) TSHRGAAGLAPOLBMAOA
SCHEMBL29618172 1.00 TSHR (0.52) TSHRGAAGLAPOLBMAOA
SCHEMBL28252501 0.95 TSHR (0.47) TSHRGAAGLAPOLBMAOA
SCHEMBL29404322 0.92 GAA (0.59) TSHRGAAGLAPOLBMAOA
SCHEMBL436804 0.92 GAA (0.59) TSHRGAAGLAPOLBMAOA
SCHEMBL19031861 0.91 TSHR (0.52) TSHRGAAGLAPOLBMAOA
SCHEMBL31402349 0.91 TSHR (0.52) TSHRGAAGLAPOLBMAOA
SCHEMBL15891163 0.91 TSHR (0.43) TSHRGAAGLAPOLBMAOA
Hydrochloric Acid SCHEMBL8863493 0.90 GAA (0.57) TSHRGAAGLAPOLBMAOA
SCHEMBL2795067 0.90 MEN1 (0.46) TSHRGAAGLAPOLBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 397 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456380-B Self-repairing and recyclable polyimide insulating film and preparation method and application thereof 北京科技大学 2023-02-03 CN claimed
CN-115625913-A Preparation method of thermoplastic polyimide composite material winding layer IV-shaped gas cylinder 佛山仙湖实验室 2023-01-20 CN claimed
US-20220267539-A1 Aromatic Polyamide Films for Transparent Flexible Substrates AKRON POLYMER SYSTEMS, INC. 2022-08-25 US claimed
CN-111808423-B Polyimide film with high heat resistance and low thermal expansion coefficient and preparation method thereof 浙江中科玖源新材料有限公司 2022-05-20 CN claimed
CN-114456380-A Self-repairing and recyclable polyimide insulating film and preparation method and application thereof 北京科技大学 2022-05-10 CN claimed
US-11046825-B2 Aromatic polyamide films for transparent flexible substrates AKRON POLYMER SYSTEMS, INC. 2021-06-29 US claimed
CN-110951099-B Polyimide film, preparation method thereof and base film of radio frequency flexible printed circuit 中天电子材料有限公司 2020-09-25 CN claimed
CN-110951099-A Polyimide film, preparation method thereof and base film of radio frequency flexible printed circuit 中天电子材料有限公司 2020-04-03 CN claimed
CN-110092908-A A kind of Kapton and its preparation method and application 中国科学院化学研究所 2019-08-06 CN claimed
CN-110066407-A A kind of high flame-retardant resin film and preparation method thereof 东华大学 2019-07-30 CN claimed
CN-102634022-B Colorless highly-transparent polyimide film as well as preparation method and application thereof CHINESE ACAD INST CHEMISTRY 2014-03-12 CN claimed
EP-2688942-A2 AROMATIC POLYAMIDE FILMS FOR TRANSPARENT FLEXIBLE SUBSTRATES Akron Polymer Systems, Inc. (US) 2014-01-29 EP claimed
WO-2012129422-A9 AROMATIC POLYAMIDE FILMS FOR TRANSPARENT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. (US) 2013-02-21 WO claimed
US-20120244330-A1 AROMATIC POLYAMIDE FILMS FOR TRANSPARENT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. 2012-09-27 US claimed
WO-2012129422-A2 AROMATIC POLYAMIDE FILMS FOR TRANSPARENT FLEXIBLE SUBSTRATES AKRON POLYMER SYSTEMS, INC. (US) 2012-09-27 WO claimed
JP-2009506349-A 2009-02-12 JP claimed
US-7459047-B2 Preparation of flexible copper foil/polyimide laminate SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-02 US claimed
EP-1904603-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS Akron Polymer Systems (US) 2008-04-02 EP claimed
WO-2007011911-A2 POLY(ARYLETHERIMIDES) FOR NEGATIVE BIREFRINGENT FILMS FOR LCDS AKRON POLYMER SYSTEMS (US) 2007-01-25 WO claimed
US-5601905-A Laminate for insulation protection of circuit boards NIPPON STEEL CHEMICAL CO., LTD. (JP) 1997-02-11 US claimed