Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.74 |
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.74 |
| ▸ | RAB9A | P51151 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.58 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496805 | 1.00 | MAPT (0.74) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL18112016 | 0.87 | MAPT (0.58) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL18112017 | 0.87 | MAPT (0.58) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL18112018 | 0.87 | MAPT (0.58) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL6507432 | 0.85 | MAPT (0.66) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL6507430 | 0.85 | MAPT (0.66) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL1405552 | 0.82 | MAPT (0.70) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL1405551 | 0.82 | MAPT (0.70) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL25201960 | 0.82 | MAPT (1.00) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL16095871 | 0.82 | MAPT (0.56) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |
| WO-2005016883-A2 | ACRYLAMIDE DERIVATIVES AS VLA-1 INTEGRIN ANTAGONISTS AND USES THEREOF | ICOS CORPORATION (US) | 2005-02-24 | — | — | WO | disclosed |