Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.48 |
| ▸ | PPARD | Q03181 | 13/20 | 0.48 |
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6497593 | 1.00 | PPARA (0.48) | PPARAPPARDPPARGMMP1RAB9A | |
| SCHEMBL6501010 | 0.92 | MMP1 (0.48) | PPARAPPARDPPARGMMP1ALDH1A1 | |
| SCHEMBL6501017 | 0.92 | MMP1 (0.48) | PPARAPPARDPPARGMMP1ALDH1A1 | |
| SCHEMBL6503992 | 0.89 | PPARA (0.46) | PPARAPPARDPPARGMMP1POLB | |
| SCHEMBL6503985 | 0.89 | PPARA (0.46) | PPARAPPARDPPARGMMP1POLB | |
| SCHEMBL6503176 | 0.88 | PPARA (0.41) | PPARAPPARDPPARGMMP1 | |
| SCHEMBL6495621 | 0.88 | PPARA (0.45) | PPARAPPARDPPARGMMP1POLB | |
| SCHEMBL6503180 | 0.88 | PPARA (0.41) | PPARAPPARDPPARGMMP1 | |
| SCHEMBL6495628 | 0.88 | PPARA (0.45) | PPARAPPARDPPARGMMP1POLB | |
| SCHEMBL6502803 | 0.87 | PPARA (0.46) | PPARAPPARDPPARGMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884821-B1 | Carboxylic acid derivatives and drugs containing the same | EISAI CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1216980-A1 | CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |